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    not3 CCR4-Not complex subunit Not3/5 [ Schizosaccharomyces pombe (fission yeast) ]

    Gene ID: 2542126, updated on 18-Sep-2024

    Summary

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    Official Symbol
    not3
    Official Full Name
    CCR4-Not complex subunit Not3/5
    Primary source
    PomBase:SPAC1B3.05
    Locus tag
    SPOM_SPAC1B3.05
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Schizosaccharomyces pombe (strain: 972h-)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
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    Genomic context

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    See not3 in Genome Data Viewer
    Location:
    chromosome: I
    Exon count:
    4
    Sequence:
    Chromosome: I; NC_003424.3 (4934571..4937012)

    Chromosome I - NC_003424.3Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene GTPase GUF1 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene UbiE family methyltransferase Neighboring gene ncRNA Neighboring gene ESCRT I complex subunit Vps28

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003424.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The architecture of the Schizosaccharomyces pombe CCR4-NOT complex. Ukleja M, et al. Nat Commun, 2016 Jan 25. PMID 26804377, Free PMC Article
    2. RNA-binding proteins distinguish between similar sequence motifs to promote targeted deadenylation by Ccr4-Not. Webster MW, et al. Elife, 2019 Jan 2. PMID 30601114, Free PMC Article
    3. mRNA Deadenylation Is Coupled to Translation Rates by the Differential Activities of Ccr4-Not Nucleases. Webster MW, et al. Mol Cell, 2018 Jun 21. PMID 29932902, Free PMC Article
    4. Ubiquitination-dependent control of sexual differentiation in fission yeast. Simonetti F, et al. Elife, 2017 Aug 25. PMID 28841135, Free PMC Article
    5. Enhancer of Rudimentary Cooperates with Conserved RNA-Processing Factors to Promote Meiotic mRNA Decay and Facultative Heterochromatin Assembly. Sugiyama T, et al. Mol Cell, 2016 Mar 3. PMID 26942678, Free PMC Article

    See all (24) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by PomBase

    Function Evidence Code Pubs
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in nuclear-transcribed mRNA poly(A) tail shortening IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in nuclear-transcribed mRNA poly(A) tail shortening IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of CCR4-NOT complex IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    part_of CCR4-NOT core complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of CCR4-NOT core complex IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    is_active_in P-body IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in cytosol HDA PubMed 

    General protein information

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    Preferred Names
    CCR4-Not complex subunit Not3/5

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003424.3 Reference assembly

      Range
      4934571..4937012
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001020217.3 → NP_594789.2  CCR4-Not complex subunit Not3/5 [Schizosaccharomyces pombe]

      See identical proteins and their annotated locations for NP_594789.2

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      O13870
      Conserved Domains (3) summary
      COG5665
      Location:12 → 636
      COG5665; CCR4-NOT transcriptional regulation complex, NOT5 subunit [Transcription]
      pfam04065
      Location:2 → 228
      Not3; Not1 N-terminal domain, CCR4-Not complex component
      pfam04153
      Location:505 → 629
      NOT2_3_5; NOT2 / NOT3 / NOT5 family
    Nucleotide Protein
    Heading Accession and Version

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