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    gih35 ATP-dependent RNA helicase [ Schizosaccharomyces pombe (fission yeast) ]

    Gene ID: 2542874, updated on 14-Nov-2024

    Summary

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    Official Symbol
    gih35
    Official Full Name
    ATP-dependent RNA helicase
    Primary source
    PomBase:SPAC20H4.09
    Locus tag
    SPOM_SPAC20H4.09
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Schizosaccharomyces pombe (strain: 972h-)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
    Also known as
    dhx35
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    Genomic context

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    See gih35 in Genome Data Viewer
    Location:
    chromosome: I
    Exon count:
    9
    Sequence:
    Chromosome: I; NC_003424.3 (2126057..2128359)

    Chromosome I - NC_003424.3Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene DNA recombination mediator, RecA family ATPase Rad57/Rhp57 Neighboring gene phosphatase activator Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ubiquitin-protein ligase E4

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003424.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Identification of proteins associated with splicing factors Ntr1, Ntr2, Brr2 and Gpl1 in the fission yeast Schizosaccharomyces pombe. Cipakova I, et al. Cell Cycle, 2019 Jul. PMID 31219728, Free PMC Article
    2. The proper splicing of RNAi factors is critical for pericentric heterochromatin assembly in fission yeast. Kallgren SP, et al. PLoS Genet, 2014. PMID 24874881, Free PMC Article
    3. Sde2 is an intron-specific pre-mRNA splicing regulator activated by ubiquitin-like processing. Thakran P, et al. EMBO J, 2018 Jan 4. PMID 28947618, Free PMC Article
    4. Defining the Functional Interactome of Spliceosome-Associated G-Patch Protein Gpl1 in the Fission Yeast Schizosaccharomyces pombe. Selicky T, et al. Int J Mol Sci, 2022 Oct 24. PMID 36361590, Free PMC Article
    5. Systematic two-hybrid and comparative proteomic analyses reveal novel yeast pre-mRNA splicing factors connected to Prp19. Ren L, et al. PLoS One, 2011 Feb 28. PMID 21386897, Free PMC Article

    See all (16) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by PomBase

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables RNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables RNA helicase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in mRNA cis splicing, via spliceosome IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in mRNA splicing, via spliceosome IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    part_of catalytic step 2 spliceosome IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in cytosol HDA PubMed 
    is_active_in nucleus HDA PubMed 
    part_of spliceosomal complex IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    ATP-dependent RNA helicase

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003424.3 Reference assembly

      Range
      2126057..2128359
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001019060.2 → NP_593629.1  ATP-dependent RNA helicase [Schizosaccharomyces pombe]

      See identical proteins and their annotated locations for NP_593629.1

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      Q9HE06
      Conserved Domains (5) summary
      smart00487
      Location:16 → 208
      DEXDc; DEAD-like helicases superfamily
      smart00847
      Location:426 → 510
      HA2; Helicase associated domain (HA2) Add an annotation
      cd00046
      Location:42 → 179
      DEXDc; DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
      pfam00271
      Location:221 → 356
      Helicase_C; Helicase conserved C-terminal domain
      pfam07717
      Location:569 → 639
      OB_NTP_bind; Oligonucleotide/oligosaccharide-binding (OB)-fold
    Nucleotide Protein
    Heading Accession and Version

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