CD40LG CD40 ligand [Bos taurus (domestic cattle)] - Gene

Summary

Official Symbol: CD40LGprovided by VGNC
Official Full Name: CD40 ligandprovided by VGNC
Primary source: VGNC:VGNC:27034
See related: BGD:BT11698; Ensembl:ENSBTAG00000051078
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Bos taurus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
Also known as: TNFSF5
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Genomic context

Location:: chromosome: Un

Exon count:: 5

Annotation release	Status	Assembly	Chr	Location
RS_2024_12	current	ARS-UCD2.0 (GCF_002263795.3)	Unplaced Scaffold	NW_020192292.1 (8251624..8263447, complement)

NW_020192292.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NW_020192292 Unplaced Scaffold Reference ARS-UCD2.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Dominette sequence data
BioProject: PRJNA294306
Analysis date: Tue Dec 17 08:57:05 2024

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Results demonstrated greater CD40 and CD40L expression on fresh mononuclear leukocytes obtained from animals in the clinical stage of Johne's Disease.
Title: Clinical disease upregulates expression of CD40 and CD40 ligand on peripheral blood mononuclear cells from cattle naturally infected with Mycobacterium avium subsp. paratuberculosis.

Submit: New GeneRIF Correction

General gene information

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Markers

CD40LG (e-PCR)
- UniSTS:506648

TNFSF5 (e-PCR)
- UniSTS:279204

Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables CD40 receptor binding	IEA Inferred from Electronic Annotation more info	PubMed
enables tumor necrosis factor receptor binding	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in immune response	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in membrane	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: CD40 ligand

Names: CD40 ligand (TNF superfamily, member 5, hyper-IgM syndrome); CD40-L; human : hyper-IgM syndrome; tumor necrosis factor (ligand) superfamily, member 5

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.