COL10A1 collagen type X alpha 1 chain [Bos taurus (domestic cattle)] - Gene

Summary

Official Symbol: COL10A1provided by VGNC
Official Full Name: collagen type X alpha 1 chainprovided by VGNC
Primary source: VGNC:VGNC:27553
See related: BGD:BT11784; Ensembl:ENSBTAG00000003078
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Bos taurus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
Annotation information: Annotation category: partial on reference assembly
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 9

Exon count:: 3

Annotation release	Status	Assembly	Chr	Location
RS_2024_12	current	ARS-UCD2.0 (GCF_002263795.3)	9	NC_037336.1 (34539788..34547373)

Chromosome 9 - NC_037336.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_037336.1 Chromosome 9 Reference ARS-UCD2.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Dominette sequence data
BioProject: PRJNA294306
Analysis date: Tue Dec 17 08:57:05 2024

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

The 4.6 kb promoter is able to drive specific expression of Col10a1 in hypertrophic cartilage.
Title: A highly conserved enhancer in mammalian type X collagen genes drives high levels of tissue-specific expression in hypertrophic cartilage in vitro and in vivo.
TSG is an important modulator of BMP-regulated induced collagen II and X expression and cartilage development and chondrocyte differentiation
Title: Twisted gastrulation modulates bone morphogenetic protein-induced collagen II and X expression in chondrocytes in vitro and in vivo.

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General gene information

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Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables protein binding	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: collagen alpha-1(X) chain

Names: collagen, type X, alpha 1 (Schmid metaphyseal chondrodysplasia); type X collagen alpha 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_174634.1 → NP_777059.1 collagen alpha-1(X) chain precursor

See identical proteins and their annotated locations for NP_777059.1

Status: PROVISIONAL

Source sequence(s)

X53556

UniProtKB/Swiss-Prot

P23206

UniProtKB/TrEMBL

F1MZ30

Related

ENSBTAP00000004006.5, ENSBTAT00000004006.5

Conserved Domains (2) summary

smart00110
Location:539 → 674

C1Q; Complement component C1q domain

pfam01391
Location:299 → 358

Collagen; Collagen triple helix repeat (20 copies)