U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination
    • Showing Current items.

    BOLA-DMA major histocompatibility complex, class II, DM alpha [ Bos taurus (domestic cattle) ]

    Gene ID: 282490, updated on 1-Jan-2025

    Summary

    Go to the top of the page Help
    Gene symbol
    BOLA-DMA
    Gene description
    major histocompatibility complex, class II, DM alpha
    See related
    Ensembl:ENSBTAG00000015730
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Also known as
    DMA
    Orthologs
    human mouse all
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See BOLA-DMA in Genome Data Viewer
    Location:
    chromosome: 23
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    RS_2024_12 current ARS-UCD2.0 (GCF_002263795.3) 23 NC_037350.1 (7263695..7282465, complement)

    Chromosome 23 - NC_037350.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC112443813 Neighboring gene major histocompatibility complex, class II, DM beta Neighboring gene bromodomain containing 2 Neighboring gene major histocompatibility complex, class II, DO alpha

    Genomic regions, transcripts, and products

    Go to the top of the page Help
    Genomic Sequence:
    NC_037350.1 Chromosome 23 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Expression

    Go to the top of the page Help
    • Project title: Dominette sequence data
    • BioProject: PRJNA294306
    • Analysis date: Tue Dec 17 08:57:05 2024

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Nucleotide sequences and the molecular evolution of the DMA and DMB genes of the bovine major histocompatibility complex. Niimi M, et al. Biochem Biophys Res Commun, 1995 Dec 14. PMID 7503731
    2. Physical assignment of the bovine MHC class IIa and class IIb genes. Hess M, et al. Cytogenet Cell Genet, 1999. PMID 10449907
    3. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

    Go to the top of the page

    General gene information

    Go to the top of the page Help

    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Process Evidence Code Pubs
    involved_in antigen processing and presentation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in immune response IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of MHC class II protein complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

    Go to the top of the page Help
    Preferred Names
    HLA class II histocompatibility antigen, DM alpha chain
    Names
    MHC class II antigen
    major histocompatibility complex, class II, DM alpha-chain, expressed
    major histocompatibility complex, class II, DMA

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001435172.1 → NP_001422101.1  HLA class II histocompatibility antigen, DM alpha chain precursor

      Status: VALIDATED

      Source sequence(s)
      NKLS02000023

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2024_12

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037350.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      7263695..7282465 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_059880215.1 → XP_059736198.1  HLA class II histocompatibility antigen, DM alpha chain isoform X2

      UniProtKB/TrEMBL
      A0AAA9T4Q8
      Related
      ENSBTAP00000082691.1, ENSBTAT00000115907.1

    2. XM_059880214.1 → XP_059736197.1  HLA class II histocompatibility antigen, DM alpha chain isoform X2

      UniProtKB/TrEMBL
      A0AAA9T4Q8

    Suppressed Reference Sequence(s)

    The following Reference Sequences have been suppressed. Explain

    1. NM_001012674.2: Suppressed sequence

      Description
      NM_001012674.2: This RefSeq was removed because it is a nonsense-mediated mRNA decay (NMD) candidate.
    Nucleotide Protein Strain
    Heading Accession and Version

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Molecular Biology Databases
    Research Materials