TRBV6-2 T cell receptor beta variable 6-2 [Homo sapiens (human)] - Gene

Summary

Official Symbol: TRBV6-2provided by HGNC
Official Full Name: T cell receptor beta variable 6-2provided by HGNC
Primary source: HGNC:HGNC:12227
See related: IMGT/GENE-DB:TRBV6-2; AllianceGenome:HGNC:12227
Gene type: other
RefSeq status: VALIDATED
Organism: Homo sapiens
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as: TRBV62; TCRBV6S2; TCRBV13S2; TCRBV13S2A1T
Summary: Predicted to be involved in cell surface receptor signaling pathway. Predicted to be part of T cell receptor complex. Predicted to be active in plasma membrane. [provided by Alliance of Genome Resources, Nov 2024]
Annotation information: Annotation category: only annotated on alternate loci in reference assembly
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Genomic context

Location:: 7q34

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCh38.p14 (GCF_000001405.40)	7 (ALT_REF_LOCI_1)	NT_187562.1 (311143..311575)
RS_2024_08	current	T2T-CHM13v2.0 (GCF_009914755.1)	7	NC_060931.1 (143664288..143664720)
RS_2024_09	previous assembly	GRCh37.p13 (GCF_000001405.25)	7 (PATCHES)	NW_003571040.1 (491214..491646)

NT_187562.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

This is the first report demonstrating the power of T-cell receptor-V beta repertoire analysis by flow cytometry in biopsies as a basis for peripheral T-cell lymphoma diagnosis.
Title: Accurate detection of the tumor clone in peripheral T-cell lymphoma biopsies by flow cytometric analysis of TCR-Vβ repertoire.

Submit: New GeneRIF Correction

Variation

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General gene information

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NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.