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    Arglu1 arginine and glutamate rich 1 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 290912, updated on 9-Dec-2024

    Summary

    Official Symbol
    Arglu1provided by RGD
    Official Full Name
    arginine and glutamate rich 1provided by RGD
    Primary source
    RGD:1310061
    See related
    EnsemblRapid:ENSRNOG00000024142 AllianceGenome:RGD:1310061
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    RGD1310061
    Summary
    Predicted to enable nuclear receptor coactivator activity and pre-mRNA binding activity. Predicted to be involved in regulation of alternative mRNA splicing, via spliceosome. Predicted to be located in cytosol and nuclear speck. Predicted to be active in mitochondrion and nucleoplasm. Orthologous to human ARGLU1 (arginine and glutamate rich 1). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Thymus (RPKM 401.5), Spleen (RPKM 302.4) and 9 other tissues See more
    Orthologs
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    Genomic context

    See Arglu1 in Genome Data Viewer
    Location:
    16q12.5
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 16 NC_086034.1 (87455097..87479148)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 16 NC_051351.1 (80753300..80777350)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 16 NC_005115.4 (86600877..86625084)

    Chromosome 16 - NC_086034.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC120097574 Neighboring gene uncharacterized LOC134482428 Neighboring gene IKAROS family zinc finger 5 like 1 Neighboring gene ephrin B2 Neighboring gene sushi domain containing 3, pseudogene 1

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    General gene information

    Markers

    Clone Names

    • MGC109359, MGC156517

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables nuclear receptor coactivator activity ISO
    Inferred from Sequence Orthology
    more info
     
    enables nuclear receptor coactivator activity ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    enables pre-mRNA binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables pre-mRNA binding ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    Process Evidence Code Pubs
    involved_in RNA splicing IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in mRNA processing IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in positive regulation of DNA-templated transcription IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in regulation of alternative mRNA splicing, via spliceosome ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in regulation of alternative mRNA splicing, via spliceosome ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    Component Evidence Code Pubs
    located_in chromosome IEA
    Inferred from Electronic Annotation
    more info
     
    located_in cytosol IEA
    Inferred from Electronic Annotation
    more info
     
    located_in cytosol ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in mitochondrion IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in mitochondrion ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nuclear speck ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nuclear speck ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    is_active_in nucleoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    arginine and glutamate-rich protein 1

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001024972.2NP_001020143.1  arginine and glutamate-rich protein 1

      See identical proteins and their annotated locations for NP_001020143.1

      Status: PROVISIONAL

      Source sequence(s)
      JAXUCZ010000016
      UniProtKB/Swiss-Prot
      A0JPJ8, Q5BJT0
      Related
      ENSRNOP00000054160.2, ENSRNOT00000057347.5
      Conserved Domains (1) summary
      pfam15346
      Location:128267
      ARGLU; Arginine and glutamate-rich 1

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086034.1 Reference GRCr8

      Range
      87455097..87479148
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    RNA

    1. XR_010058287.1 RNA Sequence