Alg5 ALG5, dolichyl-phosphate beta-glucosyltransferase [Rattus norvegicus (Norway rat)] - Gene

Summary

Official Symbol: Alg5provided by RGD
Official Full Name: ALG5, dolichyl-phosphate beta-glucosyltransferaseprovided by RGD
Primary source: RGD:1308900
See related: EnsemblRapid:ENSRNOG00000058694 AllianceGenome:RGD:1308900
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary: Predicted to enable dolichyl-phosphate beta-glucosyltransferase activity. Predicted to be involved in dolichol-linked oligosaccharide biosynthetic process. Predicted to act upstream of or within determination of left/right symmetry. Predicted to be active in cytoplasmic side of rough endoplasmic reticulum membrane. Human ortholog(s) of this gene implicated in polycystic kidney disease 7. Orthologous to human ALG5 (ALG5 dolichyl-phosphate beta-glucosyltransferase). [provided by Alliance of Genome Resources, Dec 2024]
Expression: Biased expression in Adrenal (RPKM 98.2), Liver (RPKM 90.5) and 9 other tissues See more
Orthologs: human mouse all
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Genomic context

Location:: 2q26

Exon count:: 11

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	2	NC_086020.1 (141087126..141101397)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	2	NC_051337.1 (138936998..138951228)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	2	NC_005101.4 (143932242..143946472)

Chromosome 2 - NC_086020.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
BioProject: PRJNA238328
Publication: PMID 24510058
Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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GeneRIFs: Gene References Into Functions

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General gene information

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Markers

RH139993 (e-PCR)
- UniSTS:222075

RH129855 (e-PCR)
- UniSTS:213143

D3Mit275 (e-PCR), detects polymorphism
- UniSTS:129703

RH130137 (e-PCR)
- UniSTS:213424

Gene Ontology Provided by RGD

Function	Evidence Code	Pubs
enables dolichyl-phosphate beta-glucosyltransferase activity	ISO Inferred from Sequence Orthology more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within determination of left/right symmetry	ISO Inferred from Sequence Orthology more info
involved_in dolichol-linked oligosaccharide biosynthetic process	ISO Inferred from Sequence Orthology more info
involved_in protein N-linked glycosylation	ISO Inferred from Sequence Orthology more info

Component	Evidence Code	Pubs
is_active_in cytoplasmic side of rough endoplasmic reticulum membrane	ISO Inferred from Sequence Orthology more info

General protein information

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Preferred Names: dolichyl-phosphate beta-glucosyltransferase

Names: asparagine-linked glycosylation 5 homolog (S. cerevisiae, dolichyl-phosphate beta-glucosyltransferase); asparagine-linked glycosylation 5 homolog (yeast, dolichyl-phosphate beta-glucosyltransferase); asparagine-linked glycosylation 5, dolichyl-phosphate beta-glucosyltransferase homolog

NP_001020578.1

EC 2.4.1.117

XP_006232395.1

EC 2.4.1.117

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.