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    Nudt14 nudix hydrolase 14 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 299346, updated on 9-Dec-2024

    Summary

    Official Symbol
    Nudt14provided by RGD
    Official Full Name
    nudix hydrolase 14provided by RGD
    Primary source
    RGD:1310583
    See related
    EnsemblRapid:ENSRNOG00000014362 AllianceGenome:RGD:1310583
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to enable ADP-ribose diphosphatase activity; UDP-sugar diphosphatase activity; and identical protein binding activity. Predicted to be involved in nucleoside phosphate metabolic process and ribose phosphate metabolic process. Orthologous to human NUDT14 (nudix hydrolase 14). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Kidney (RPKM 163.5), Lung (RPKM 131.9) and 9 other tissues See more
    Orthologs
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    Genomic context

    See Nudt14 in Genome Data Viewer
    Location:
    6q32
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 6 NC_086024.1 (137831382..137838370, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 6 NC_051341.1 (132010309..132017298, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 6 NC_005105.4 (137738150..137745143, complement)

    Chromosome 6 - NC_086024.1Genomic Context describing neighboring genes Neighboring gene keratin-associated protein 5-9-like Neighboring gene jagged canonical Notch ligand 2 Neighboring gene BRF1 general transcription factor IIIB subunit Neighboring gene BTB domain containing 6 Neighboring gene phosphofurin acidic cluster sorting protein 2 Neighboring gene uncharacterized LOC134479482

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    General gene information

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables ADP-ribose diphosphatase activity ISO
    Inferred from Sequence Orthology
    more info
     
    enables UDP-sugar diphosphatase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables UDP-sugar diphosphatase activity ISO
    Inferred from Sequence Orthology
    more info
     
    enables identical protein binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    involved_in nucleoside phosphate metabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in ribose phosphate metabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
     

    General protein information

    Preferred Names
    uridine diphosphate glucose pyrophosphatase NUDT14
    Names
    nudix (nucleoside diphosphate linked moiety X)-type motif 14
    nudix-type motif 14
    uridine diphosphate glucose pyrophosphatase
    NP_001100230.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001106760.1NP_001100230.1  uridine diphosphate glucose pyrophosphatase NUDT14

      See identical proteins and their annotated locations for NP_001100230.1

      Status: PROVISIONAL

      Source sequence(s)
      CH474034
      UniProtKB/TrEMBL
      A0A8I6G8A4, A6KBX1, D4A1D4
      Related
      ENSRNOP00000019550.5, ENSRNOT00000019550.8
      Conserved Domains (1) summary
      TIGR00052
      Location:23210
      TIGR00052; nudix-type nucleoside diphosphatase, YffH/AdpP family

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086024.1 Reference GRCr8

      Range
      137831382..137838370 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)