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    CG32767 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 31430, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG32767provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0052767
    Locus tag
    Dmel_CG32767
    See related
    AllianceGenome:FB:FBgn0052767
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    BcDNA:GM08530; CG5086; CG5113; Dmel\CG32767; i7; LD34931
    Summary
    Predicted to enable DNA-binding transcription activator activity, RNA polymerase II-specific; DNA-binding transcription repressor activity, RNA polymerase II-specific; and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in negative regulation of transcription by RNA polymerase II. Predicted to be located in nucleolus. Predicted to be active in nucleus. Is expressed in organism; wing hinge primordium; and wing pouch. Orthologous to several human genes including ZNF136 (zinc finger protein 136); ZNF333 (zinc finger protein 333); and ZNF34 (zinc finger protein 34). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG32767 in Genome Data Viewer
    Location:
    4E2-4E2; 1-10 cM
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) X NC_004354.4 (5071027..5084768, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) X NC_004354.3 (4965060..4978801, complement)

    Chromosome X - NC_004354.4Genomic Context describing neighboring genes Neighboring gene long non-coding RNA:CR44833 Neighboring gene uncharacterized protein Neighboring gene ovo Neighboring gene uncharacterized protein Neighboring gene rugose Neighboring gene Regulatory particle non-ATPase 13-related Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The microRNA miR-8 is a conserved negative regulator of Wnt signaling. Kennell JA, et al. Proc Natl Acad Sci U S A, 2008 Oct 7. PMID 18824696, Free PMC Article
    2. Mutations in the transcription elongation factor SPT5 disrupt a reporter for dosage compensation in Drosophila. Prabhakaran M, et al. PLoS Genet, 2012. PMID 23209435, Free PMC Article
    3. MSL complex is attracted to genes marked by H3K36 trimethylation using a sequence-independent mechanism. Larschan E, et al. Mol Cell, 2007 Oct 12. PMID 17936709
    4. Genome-wide RNAi analysis of JAK/STAT signaling components in Drosophila. Baeg GH, et al. Genes Dev, 2005 Aug 15. PMID 16055650, Free PMC Article
    5. MicroRNA-277 modulates the neurodegeneration caused by Fragile X premutation rCGG repeats. Tan H, et al. PLoS Genet, 2012. PMID 22570635, Free PMC Article

    See all (40) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables DNA-binding transcription activator activity, RNA polymerase II-specific IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables DNA-binding transcription repressor activity, RNA polymerase II-specific ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables RNA polymerase II cis-regulatory region sequence-specific DNA binding ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Process Evidence Code Pubs
    involved_in negative regulation of transcription by RNA polymerase II ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    involved_in regulation of transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    located_in nucleolus ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG32767-PC
    CG32767-PD
    CG32767-PE
    CG32767-PF
    CG32767-PG
    CG32767-PH

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_004354.4 Reference assembly

      Range
      5071027..5084768 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001272321.1 → NP_001259250.1  uncharacterized protein Dmel_CG32767, isoform H [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001259250.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q7YU56, Q9W4E8
      Conserved Domains (3) summary
      sd00017
      Location:622 → 642
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:648 → 670
      zf-C2H2; Zinc finger, C2H2 type
      pfam13465
      Location:662 → 684
      zf-H2C2_2; Zinc-finger double domain

    2. NM_206628.2 → NP_996351.1  uncharacterized protein Dmel_CG32767, isoform D [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_996351.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q7YU56, Q9W4E8
      Conserved Domains (3) summary
      sd00017
      Location:622 → 642
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:648 → 670
      zf-C2H2; Zinc finger, C2H2 type
      pfam13465
      Location:662 → 684
      zf-H2C2_2; Zinc-finger double domain

    3. NM_001272320.1 → NP_001259249.1  uncharacterized protein Dmel_CG32767, isoform G [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001259249.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      M9PGP7, Q7YU56
      Conserved Domains (3) summary
      sd00017
      Location:622 → 642
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:648 → 670
      zf-C2H2; Zinc finger, C2H2 type
      pfam13465
      Location:662 → 684
      zf-H2C2_2; Zinc-finger double domain

    4. NM_001169204.2 → NP_001162675.1  uncharacterized protein Dmel_CG32767, isoform F [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001162675.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q7YU56, Q9W4E8
      Conserved Domains (3) summary
      sd00017
      Location:622 → 642
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:648 → 670
      zf-C2H2; Zinc finger, C2H2 type
      pfam13465
      Location:662 → 684
      zf-H2C2_2; Zinc-finger double domain

    5. NM_131975.5 → NP_572203.2  uncharacterized protein Dmel_CG32767, isoform E [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_572203.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q7YU56, Q9W4E8
      Related
      FBpp0291328
      Conserved Domains (3) summary
      sd00017
      Location:622 → 642
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:648 → 670
      zf-C2H2; Zinc finger, C2H2 type
      pfam13465
      Location:662 → 684
      zf-H2C2_2; Zinc-finger double domain

    6. NM_001169203.2 → NP_001162674.1  uncharacterized protein Dmel_CG32767, isoform C [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001162674.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q7YU56, Q9W4E8
      Conserved Domains (3) summary
      sd00017
      Location:622 → 642
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:648 → 670
      zf-C2H2; Zinc finger, C2H2 type
      pfam13465
      Location:662 → 684
      zf-H2C2_2; Zinc-finger double domain
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    M9PGP7 M9PGP7
    Q7YU56 Q7YU56
    Q8T947 Q8T947
    Q95RF1 Q95RF1
    Q9W4E8 Q9W4E8

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