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    Pop1 POP1 ribonuclease P/MRP subunit [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 31475, updated on 9-Dec-2024

    Summary

    Official Symbol
    Pop1provided by FlyBase
    Official Full Name
    POP1 ribonuclease P/MRP subunitprovided by FlyBase
    Primary source
    FLYBASE:FBgn0026702
    Locus tag
    Dmel_CG32763
    See related
    AllianceGenome:FB:FBgn0026702
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    BcDNA:LD21623; CG32763; CG4129; Dmel\CG32763; l(1)G0045; l(1)G0312
    Summary
    Predicted to enable ribonuclease P RNA binding activity. Predicted to be involved in rRNA processing and tRNA 5'-leader removal. Predicted to be part of nucleolar ribonuclease P complex and ribonuclease MRP complex. Is expressed in organism. Human ortholog(s) of this gene implicated in anauxetic dysplasia 2. Orthologous to human POP1 (POP1 homolog, ribonuclease P/MRP subunit). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
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    Genomic context

    See Pop1 in Genome Data Viewer
    Location:
    5A8-5A8; 1-12 cM
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) X NC_004354.4 (5622648..5625493)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) X NC_004354.3 (5516681..5519526)

    Chromosome X - NC_004354.4Genomic Context describing neighboring genes Neighboring gene Rho GTPase activating protein at 5A Neighboring gene Myosin light chain cytoplasmic Neighboring gene mir-3645 stem loop Neighboring gene Otopetrin-like a Neighboring gene Otopetrin-like c

    Genomic regions, transcripts, and products

    General gene information

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables ribonuclease P RNA binding ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    Process Evidence Code Pubs
    involved_in rRNA processing ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in tRNA 5'-leader removal IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in tRNA 5'-leader removal ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in tRNA processing IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    part_of multimeric ribonuclease P complex ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    part_of nucleolar ribonuclease P complex IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    part_of nucleolar ribonuclease P complex IEA
    Inferred from Electronic Annotation
    more info
     
    part_of ribonuclease MRP complex IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    part_of ribonuclease MRP complex IEA
    Inferred from Electronic Annotation
    more info
     
    part_of ribonuclease MRP complex ISS
    Inferred from Sequence or Structural Similarity
    more info
     

    General protein information

    Preferred Names
    POP1 ribonuclease P/MRP subunit
    Names
    CG32763-PA
    Pop1-PA
    lethal (1) G0045

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_004354.4 Reference assembly

      Range
      5622648..5625493
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_132008.4NP_572236.3  POP1 ribonuclease P/MRP subunit [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_572236.3

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q7KVW2, Q9W4A7, Q9XZ20
      Related
      FBpp0070748
      Conserved Domains (2) summary
      pfam06978
      Location:33178
      POP1; Ribonucleases P/MRP protein subunit POP1
      pfam08170
      Location:514600
      POPLD; POPLD (NUC188) domain