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    CG32280 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 317952, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG32280provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0052280
    Locus tag
    Dmel_CG32280
    See related
    AllianceGenome:FB:FBgn0052280
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    BcDNA:GM08588; Dmel\CG32280
    Summary
    Predicted to enable zinc ion binding activity. Human ortholog(s) of this gene implicated in Charcot-Marie-Tooth disease type 1C. Orthologous to several human genes including CDIP1 (cell death inducing p53 target 1). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG32280 in Genome Data Viewer
    Location:
    63B8-63B8; 3-6 cM
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3L NT_037436.4 (3165181..3169080)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3L NT_037436.3 (3165181..3169080)

    Chromosome 3L - NT_037436.4Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene rasp Neighboring gene ASCIZ zinc finger protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Drosophila Charcot-Marie-Tooth Disease Models. Yamaguchi M, et al. Adv Exp Med Biol, 2018. PMID 29951817
    2. The Drosophila Tis11 protein and its effects on mRNA expression in flies. Choi YJ, et al. J Biol Chem, 2014 Dec 19. PMID 25342740, Free PMC Article
    3. Recent Advances in Drosophila Models of Charcot-Marie-Tooth Disease. Kitani-Morii F, et al. Int J Mol Sci, 2020 Oct 8. PMID 33049996, Free PMC Article
    4. Systematic screening of a Drosophila ORF library in vivo uncovers Wnt/Wg pathway components. Schertel C, et al. Dev Cell, 2013 Apr 29. PMID 23583758
    5. Next-generation large-scale binary protein interaction network for Drosophila melanogaster. Tang HW, et al. Nat Commun, 2023 Apr 15. PMID 37061542, Free PMC Article

    See all (26) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables zinc ion binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG32280-PA
    CG32280-PB
    CG32280-PC
    CG32280-PD

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_037436.4 Reference assembly

      Range
      3165181..3169080
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001299998.1 → NP_001286927.1  uncharacterized protein Dmel_CG32280, isoform D [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001286927.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q8IRE5
      Conserved Domains (1) summary
      pfam10601
      Location:60 → 129
      zf-LITAF-like; LITAF-like zinc ribbon domain

    2. NM_167993.2 → NP_728819.1  uncharacterized protein Dmel_CG32280, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_728819.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q8IRE5
      Related
      FBpp0072895
      Conserved Domains (1) summary
      pfam10601
      Location:60 → 129
      zf-LITAF-like; LITAF-like zinc ribbon domain

    3. NM_167992.2 → NP_728818.1  uncharacterized protein Dmel_CG32280, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_728818.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q8IRE5
      Related
      FBpp0072894
      Conserved Domains (1) summary
      pfam10601
      Location:60 → 129
      zf-LITAF-like; LITAF-like zinc ribbon domain

    4. NM_167994.1 → NP_728820.1  uncharacterized protein Dmel_CG32280, isoform C [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_728820.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q8IRE5
      Related
      FBpp0072896, FBtr0073032
      Conserved Domains (1) summary
      pfam10601
      Location:60 → 129
      zf-LITAF-like; LITAF-like zinc ribbon domain
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8IRE5 Q8IRE5
    Q95S57 Q95S57

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