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    Zfp944 zinc finger protein 944 [ Mus musculus (house mouse) ]

    Gene ID: 319615, updated on 27-Nov-2024

    Summary

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    Official Symbol
    Zfp944provided by MGI
    Official Full Name
    zinc finger protein 944provided by MGI
    Primary source
    MGI:MGI:2442394
    See related
    Ensembl:ENSMUSG00000033972 AllianceGenome:MGI:2442394
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    6330416L07Rik
    Summary
    Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. Is expressed in early conceptus; inner cell mass; and oocyte. [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Ubiquitous expression in CNS E18 (RPKM 3.8), CNS E14 (RPKM 3.3) and 28 other tissues See more
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    Genomic context

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    See Zfp944 in Genome Data Viewer
    Location:
    17 A3.3; 17 11.4 cM
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 17 NC_000083.7 (22556964..22580409, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 17 NC_000083.6 (22337983..22361428, complement)

    Chromosome 17 - NC_000083.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 52309 Neighboring gene zinc finger protein 994 Neighboring gene STARR-seq mESC enhancer starr_42025 Neighboring gene STARR-positive B cell enhancer ABC_E4195 Neighboring gene STARR-seq mESC enhancer starr_42027 Neighboring gene predicted gene 7072 Neighboring gene STARR-seq mESC enhancer starr_42028 Neighboring gene predicted gene, 53992 Neighboring gene STARR-positive B cell enhancer ABC_E5576 Neighboring gene STARR-seq mESC enhancer starr_42030 Neighboring gene zinc finger protein 758 Neighboring gene STARR-seq mESC enhancer starr_42031 Neighboring gene STARR-positive B cell enhancer ABC_E5577 Neighboring gene STARR-seq mESC enhancer starr_42032 Neighboring gene zinc finger protein 946 Neighboring gene STARR-seq mESC enhancer starr_42034 Neighboring gene eukaryotic translation elongation factor 1 gamma pseudogene

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. Resolution of cell fate decisions revealed by single-cell gene expression analysis from zygote to blastocyst. Guo G, et al. Dev Cell, 2010 Apr 20. PMID 20412781
    2. Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method. Piao Y, et al. Genome Res, 2001 Sep. PMID 11544199, Free PMC Article
    3. A systems approach reveals that the myogenesis genome network is regulated by the transcriptional repressor RP58. Yokoyama S, et al. Dev Cell, 2009 Dec. PMID 20059953, Free PMC Article
    4. Mouse brain organization revealed through direct genome-scale TF expression analysis. Gray PA, et al. Science, 2004 Dec 24. PMID 15618518
    5. Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. Zambrowicz BP, et al. Proc Natl Acad Sci U S A, 2003 Nov 25. PMID 14610273, Free PMC Article

    See all (15) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Clone Names

    • MGC117948

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables DNA-binding transcription factor activity, RNA polymerase II-specific IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in regulation of transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein LOC319615

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001355280.1 → NP_001342209.1  uncharacterized protein LOC319615

      Status: VALIDATED

      Source sequence(s)
      AC117244
      Consensus CDS
      CCDS50000.1
      UniProtKB/TrEMBL
      E9PUS4
      Conserved Domains (4) summary
      COG5048
      Location:321 → 484
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:241 → 261
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam01352
      Location:13 → 52
      KRAB; KRAB box
      pfam13465
      Location:253 → 278
      zf-H2C2_2; Zinc-finger double domain

    2. NM_176962.4 → NP_795936.2  uncharacterized protein LOC319615

      See identical proteins and their annotated locations for NP_795936.2

      Status: VALIDATED

      Source sequence(s)
      AC117244, BE133041, CJ187522
      Consensus CDS
      CCDS50000.1
      UniProtKB/TrEMBL
      E9PUS4
      Related
      ENSMUSP00000111197.3, ENSMUST00000115535.3
      Conserved Domains (4) summary
      COG5048
      Location:321 → 484
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:241 → 261
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam01352
      Location:13 → 52
      KRAB; KRAB box
      pfam13465
      Location:253 → 278
      zf-H2C2_2; Zinc-finger double domain

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000083.7 Reference GRCm39 C57BL/6J

      Range
      22556964..22580409 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_030249840.2 → XP_030105700.1  uncharacterized protein LOC319615 isoform X3

      Conserved Domains (3) summary
      COG5048
      Location:283 → 446
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:203 → 223
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam13465
      Location:215 → 240
      zf-H2C2_2; Zinc-finger double domain

    2. XM_036160643.1 → XP_036016536.1  uncharacterized protein LOC319615 isoform X2

      UniProtKB/TrEMBL
      E9PUS4
      Conserved Domains (4) summary
      COG5048
      Location:321 → 484
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:241 → 261
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam01352
      Location:13 → 52
      KRAB; KRAB box
      pfam13465
      Location:253 → 278
      zf-H2C2_2; Zinc-finger double domain

    3. XM_030249838.2 → XP_030105698.1  uncharacterized protein LOC319615 isoform X2

      UniProtKB/TrEMBL
      E9PUS4
      Conserved Domains (4) summary
      COG5048
      Location:321 → 484
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:241 → 261
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam01352
      Location:13 → 52
      KRAB; KRAB box
      pfam13465
      Location:253 → 278
      zf-H2C2_2; Zinc-finger double domain

    4. XM_036160640.1 → XP_036016533.1  uncharacterized protein LOC319615 isoform X1

      Conserved Domains (4) summary
      COG5048
      Location:341 → 504
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:261 → 281
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam01352
      Location:33 → 72
      KRAB; KRAB box
      pfam13465
      Location:273 → 298
      zf-H2C2_2; Zinc-finger double domain

    5. XM_036160641.1 → XP_036016534.1  uncharacterized protein LOC319615 isoform X1

      Conserved Domains (4) summary
      COG5048
      Location:341 → 504
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:261 → 281
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam01352
      Location:33 → 72
      KRAB; KRAB box
      pfam13465
      Location:273 → 298
      zf-H2C2_2; Zinc-finger double domain

    6. XM_036160642.1 → XP_036016535.1  uncharacterized protein LOC319615 isoform X1

      Conserved Domains (4) summary
      COG5048
      Location:341 → 504
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:261 → 281
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam01352
      Location:33 → 72
      KRAB; KRAB box
      pfam13465
      Location:273 → 298
      zf-H2C2_2; Zinc-finger double domain

    7. XM_030249836.2 → XP_030105696.1  uncharacterized protein LOC319615 isoform X2

      UniProtKB/TrEMBL
      E9PUS4
      Conserved Domains (4) summary
      COG5048
      Location:321 → 484
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:241 → 261
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam01352
      Location:13 → 52
      KRAB; KRAB box
      pfam13465
      Location:253 → 278
      zf-H2C2_2; Zinc-finger double domain

    8. XM_030249835.2 → XP_030105695.1  uncharacterized protein LOC319615 isoform X2

      UniProtKB/TrEMBL
      E9PUS4
      Conserved Domains (4) summary
      COG5048
      Location:321 → 484
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:241 → 261
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam01352
      Location:13 → 52
      KRAB; KRAB box
      pfam13465
      Location:253 → 278
      zf-H2C2_2; Zinc-finger double domain

    9. XM_030249837.2 → XP_030105697.1  uncharacterized protein LOC319615 isoform X2

      UniProtKB/TrEMBL
      E9PUS4
      Conserved Domains (4) summary
      COG5048
      Location:321 → 484
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:241 → 261
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam01352
      Location:13 → 52
      KRAB; KRAB box
      pfam13465
      Location:253 → 278
      zf-H2C2_2; Zinc-finger double domain

    10. XM_036160639.1 → XP_036016532.1  uncharacterized protein LOC319615 isoform X1

      Conserved Domains (4) summary
      COG5048
      Location:341 → 504
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:261 → 281
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam01352
      Location:33 → 72
      KRAB; KRAB box
      pfam13465
      Location:273 → 298
      zf-H2C2_2; Zinc-finger double domain

    11. XM_030249834.2 → XP_030105694.1  uncharacterized protein LOC319615 isoform X2

      UniProtKB/TrEMBL
      E9PUS4
      Conserved Domains (4) summary
      COG5048
      Location:321 → 484
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:241 → 261
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam01352
      Location:13 → 52
      KRAB; KRAB box
      pfam13465
      Location:253 → 278
      zf-H2C2_2; Zinc-finger double domain

    12. XM_036160638.1 → XP_036016531.1  uncharacterized protein LOC319615 isoform X1

      Conserved Domains (4) summary
      COG5048
      Location:341 → 504
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:261 → 281
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam01352
      Location:33 → 72
      KRAB; KRAB box
      pfam13465
      Location:273 → 298
      zf-H2C2_2; Zinc-finger double domain
    Nucleotide Protein Strain
    Heading Accession and Version

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