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    mybphb myosin binding protein Hb [ Danio rerio (zebrafish) ]

    Gene ID: 321053, updated on 4-Jan-2025

    Summary

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    Official Symbol
    mybphbprovided by ZNC
    Official Full Name
    myosin binding protein Hbprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-030131-9794
    See related
    Ensembl:ENSDARG00000003081 AllianceGenome:ZFIN:ZDB-GENE-030131-9794
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    cb36; sb:cb36; hm:zeh1059; zgc:165344
    Summary
    Predicted to be involved in sarcomere organization. Predicted to be active in M band. Is expressed in musculature system; myotome; pectoral fin musculature; segmental plate; and somite. Orthologous to human MYBPH (myosin binding protein H). [provided by Alliance of Genome Resources, Jan 2025]
    Annotation information
    Annotation category: partial on reference assembly
    Orthologs
    all
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    Genomic context

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    See mybphb in Genome Data Viewer
    Location:
    chromosome: 6
    Exon count:
    13
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 6 NC_007117.7 (55032487..55107333)
    105 previous assembly GRCz10 (GCF_000002035.5) 6 NC_007117.6 (55022674..55097520)

    Chromosome 6 - NC_007117.7Genomic Context describing neighboring genes Neighboring gene neuron navigator 1b Neighboring gene cysteine and glycine-rich protein 1b Neighboring gene uncharacterized LOC103911280 Neighboring gene synaptotagmin-2 Neighboring gene nuclear factor of activated T-cells, cytoplasmic 2 Neighboring gene mannosidase beta like

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. The Hippo pathway effector Wwtr1 regulates cardiac wall maturation in zebrafish. Lai JKH, et al. Development, 2018 May 17. PMID 29773645
    2. Dietary lysine imbalance affects muscle proteome in zebrafish (Danio rerio): a comparative 2D-DIGE study. de Vareilles M, et al. Mar Biotechnol (NY), 2012 Oct. PMID 22580902
    3. A transcriptomics analysis of the Tbx5 paralogues in zebrafish. Boyle Anderson EAT, et al. PLoS One, 2018. PMID 30532148, Free PMC Article
    4. Patterns of alternative splicing in response to cold acclimation in fish. Healy TM, et al. J Exp Biol, 2019 Mar 7. PMID 30692167
    5. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article

    See all (8) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    General gene information

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    Markers

    Homology

    Gene Ontology Provided by ZFIN

    Process Evidence Code Pubs
    involved_in sarcomere organization IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in M band IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    myosin binding protein Hb

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001100137.1 → NP_001093607.1  myosin binding protein Hb

      See identical proteins and their annotated locations for NP_001093607.1

      Status: PROVISIONAL

      Source sequence(s)
      BC146703
      UniProtKB/TrEMBL
      A0A8M1NDT3, A6H8Q3
      Related
      ENSDARP00000110377.1, ENSDART00000122794.3
      Conserved Domains (4) summary
      cd00096
      Location:447 → 513
      Ig; Immunoglobulin domain
      cd00063
      Location:124 → 205
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      pfam07679
      Location:429 → 518
      I-set; Immunoglobulin I-set domain
      cl11960
      Location:238 → 310
      Ig; Immunoglobulin domain

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007117.7 Reference GRCz11 Primary Assembly

      Range
      55032487..55107333
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version

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