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    CG14230 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 32984, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG14230provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0031062
    Locus tag
    Dmel_CG14230
    See related
    AllianceGenome:FB:FBgn0031062
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    anon-18DEe; cg14230; clone 9.42; Dmel\CG14230; Nol8
    Summary
    Predicted to enable mRNA binding activity. Predicted to be involved in mRNA splicing, via spliceosome. Predicted to be active in nuclear speck. Orthologous to human NOL8 (nucleolar protein 8). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG14230 in Genome Data Viewer
    Location:
    18E1-18E2; 1-64 cM
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) X NC_004354.4 (19704176..19706417)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) X NC_004354.3 (19598209..19600450)

    Chromosome X - NC_004354.4Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene Cell division cycle 42 Neighboring gene Threonyl-carbamoyl synthesis 4 Neighboring gene uncharacterized protein Neighboring gene meso18E Neighboring gene long non-coding RNA:CR44889 Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Isolation of mutations in the Drosophila homologues of the human Neurofibromatosis 2 and yeast CDC42 genes using a simple and efficient reverse-genetic method. Fehon RG, et al. Genetics, 1997 May. PMID 9136014, Free PMC Article
    2. Identification of New Regulators of the Oocyte-to-Embryo Transition in Drosophila. Avilés-Pagán EE, et al. G3 (Bethesda), 2020 Sep 2. PMID 32690584, Free PMC Article
    3. Interspecies analysis of MYC targets identifies tRNA synthetases as mediators of growth and survival in MYC-overexpressing cells. Zirin J, et al. Proc Natl Acad Sci U S A, 2019 Jul 16. PMID 31262815, Free PMC Article
    4. An in vivo RNA interference screen identifies gene networks controlling Drosophila melanogaster blood cell homeostasis. Avet-Rochex A, et al. BMC Dev Biol, 2010 Jun 11. PMID 20540764, Free PMC Article
    5. A functional genomics screen identifying blood cell development genes in Drosophila by undergraduates participating in a course-based research experience. Evans CJ, et al. G3 (Bethesda), 2021 Jan 18. PMID 33561251, Free PMC Article

    See all (33) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables RNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables RNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables mRNA binding ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in mRNA splicing, via spliceosome IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in nuclear speck IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG14230-PA

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_004354.4 Reference assembly

      Range
      19704176..19706417
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_134505.3 → NP_608349.1  uncharacterized protein Dmel_CG14230 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_608349.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9VWD4
      Related
      FBpp0074556
      Conserved Domains (2) summary
      COG0724
      Location:3 → 115
      RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
      cd00590
      Location:7 → 77
      RRM_SF; RNA recognition motif (RRM) superfamily
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9VWD4.2 Q9VWD4

    Gene LinkOut

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