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    CG33557 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 3346145, updated on 17-Dec-2024

    Summary

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    Official Symbol
    CG33557provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0053557
    Locus tag
    Dmel_CG33557
    See related
    AllianceGenome:FB:FBgn0053557
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG12648; Dmel\CG33557
    Summary
    Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Predicted to be involved in developmental process and regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Is expressed in dorsal median cell; larval ventral nerve cord; and organism. Orthologous to human SCX (scleraxis bHLH transcription factor) and TCF15 (transcription factor 15). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG33557 in Genome Data Viewer
    Location:
    9A4-9A4; 1-30 cM
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) X NC_004354.4 (10009210..10010049)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) X NC_004354.3 (9903243..9904082)

    Chromosome X - NC_004354.4Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene DNA replication helicase/nuclease 2 Neighboring gene Chitinase 6 Neighboring gene antisense RNA:CR45185

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Proliferation and dissemination of killer meiotic drive loci. Lai EC, et al. Curr Opin Genet Dev, 2023 Oct. PMID 37625205, Free PMC Article
    2. New members of the Drosophila Myc transcription factor subfamily revealed by a genome-wide examination for basic helix-loop-helix genes. Peyrefitte S, et al. Mech Dev, 2001 Jun. PMID 11404084
    3. Soul is a master control gene governing the development of the Drosophila prothoracic gland. Liu W, et al. Proc Natl Acad Sci U S A, 2024 Oct. PMID 39312662,
    4. The basic helix-loop-helix protein family: comparative genomics and phylogenetic analysis. Ledent V, et al. Genome Res, 2001 May. PMID 11337472, Free PMC Article
    5. Origin and diversification of the basic helix-loop-helix gene family in metazoans: insights from comparative genomics. Simionato E, et al. BMC Evol Biol, 2007 Mar 2. PMID 17335570, Free PMC Article

    See all (38) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables DNA-binding transcription factor activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    enables DNA-binding transcription factor activity, RNA polymerase II-specific IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables RNA polymerase II transcription regulatory region sequence-specific DNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables protein dimerization activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in developmental process IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in regulation of DNA-templated transcription ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    involved_in regulation of transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    located_in nucleus IC
    Inferred by Curator
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG33557-PA

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_004354.4 Reference assembly

      Range
      10009210..10010049
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001014730.2 → NP_001014730.1  uncharacterized protein Dmel_CG33557 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001014730.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q59E67
      Conserved Domains (1) summary
      smart00353
      Location:67 → 119
      HLH; helix loop helix domain
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q59E67 Q59E67

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