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    Pp1-Y2 Protein phosphatase 1, Y-linked 2 [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 3355173, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Pp1-Y2provided by FlyBase
    Official Full Name
    Protein phosphatase 1, Y-linked 2provided by FlyBase
    Primary source
    FLYBASE:FBgn0046698
    Locus tag
    Dmel_CG40448
    See related
    AllianceGenome:FB:FBgn0046698
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG40448; Dmel\CG40448; DmPp1-Y2; FBgn0046698; PP1-Y2; Pp1Y2
    Summary
    Predicted to enable protein serine/threonine phosphatase activity. Predicted to be active in cytoplasm and nucleus. Is expressed in organism and testis. [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See Pp1-Y2 in Genome Data Viewer
    Location:
    chromosome: Y
    Exon count:
    1
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) Y NC_024512.1 (3539437..3540722, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) YHet NW_001848860.1 (279861..292007)

    Chromosome Y - NC_024512.1Genomic Context describing neighboring genes Neighboring gene pseudo Neighboring gene pseudo Neighboring gene Occludin-Related Y Neighboring gene Coiled-Coils Y

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Genomic and cytological analysis of the Y chromosome of Drosophila melanogaster: telomere-derived sequences at internal regions. Abad JP, et al. Chromosoma, 2004 Dec. PMID 15616866
    2. Identification of five new genes on the Y chromosome of Drosophila melanogaster. Carvalho AB, et al. Proc Natl Acad Sci U S A, 2001 Nov 6. PMID 11687639, Free PMC Article
    3. Selection and geography shape male reproductive tract transcriptomes in Drosophila melanogaster. Cridland JM, et al. Genetics, 2023 May 4. PMID 36869688, Free PMC Article
    4. Positive and purifying selection on the Drosophila Y chromosome. Singh ND, et al. Mol Biol Evol, 2014 Oct. PMID 24974375, Free PMC Article
    5. Drosophila melanogaster Y Chromosome Genes Affect Male Sensitivity to Microbial Infections. Bartolo G, et al. Insects, 2021 Jan 5. PMID 33466347, Free PMC Article

    See all (35) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    • Annotated by Drosophila Heterochromatin Genome Project, Lawrence Berkeley National Lab, http://www.dhgp.org

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables hydrolase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables protein serine/threonine phosphatase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables protein serine/threonine phosphatase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in cytoplasm ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in nucleus ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  

    General protein information

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    Preferred Names
    protein phosphatase 1, Y-linked 2
    Names
    CG40448-PC
    Pp1-Y2-PC
    NP_001015497.4

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_024512.1 Reference assembly

      Range
      3539437..3540722 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001015497.4 → NP_001015497.4  protein phosphatase 1, Y-linked 2 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001015497.4

      Status: REVIEWED

      UniProtKB/TrEMBL
      F0JAF6, Q5K375, Q5LJN2
      Conserved Domains (2) summary
      PTZ00480
      Location:10 → 303
      PTZ00480; serine/threonine-protein phosphatase; Provisional
      cd07414
      Location:13 → 300
      MPP_PP1_PPKL; PP1, PPKL (PP1 and kelch-like) enzymes, and related proteins, metallophosphatase domain
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q5K375 Q5K375
    Q5LJN2 Q5LJN2
    Q95V51 Q95V51

    Gene LinkOut

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