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    Mrpl21 mitochondrial ribosomal protein L21 [ Mus musculus (house mouse) ]

    Gene ID: 353242, updated on 27-Nov-2024

    Summary

    Official Symbol
    Mrpl21provided by MGI
    Official Full Name
    mitochondrial ribosomal protein L21provided by MGI
    Primary source
    MGI:MGI:2660674
    See related
    Ensembl:ENSMUSG00000024829 AllianceGenome:MGI:2660674
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    L21mt; MRP-L21
    Summary
    Predicted to be a structural constituent of ribosome. Located in mitochondrion. Is expressed in several structures, including brain; early conceptus; gonad; heart; and liver. Orthologous to human MRPL21 (mitochondrial ribosomal protein L21). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Ubiquitous expression in CNS E11.5 (RPKM 10.8), large intestine adult (RPKM 8.3) and 28 other tissues See more
    Orthologs
    NEW
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    Genomic context

    See Mrpl21 in Genome Data Viewer
    Location:
    19 A; 19 3.05 cM
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 19 NC_000085.7 (3332997..3342837)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 19 NC_000085.6 (3282997..3292837)

    Chromosome 19 - NC_000085.7Genomic Context describing neighboring genes Neighboring gene Crn, crooked neck-like 1 pseudogene Neighboring gene zinc finger protein 384 pseudogene Neighboring gene immunoglobulin mu DNA binding protein 2 Neighboring gene CapStarr-seq enhancer MGSCv37_chr19:3282897-3283006 Neighboring gene microRNA 6984 Neighboring gene STARR-seq mESC enhancer starr_45314 Neighboring gene carnitine palmitoyltransferase 1a, liver Neighboring gene testis expressed metallothionein like

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Clone Names

    • MGC41352

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables RNA binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables structural constituent of ribosome IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables structural constituent of ribosome IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    involved_in mitochondrial translation NAS
    Non-traceable Author Statement
    more info
    PubMed 
    Component Evidence Code Pubs
    located_in mitochondrial inner membrane NAS
    Non-traceable Author Statement
    more info
    PubMed 
    part_of mitochondrial large ribosomal subunit IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    part_of mitochondrial large ribosomal subunit ISO
    Inferred from Sequence Orthology
    more info
     
    part_of mitochondrial large ribosomal subunit ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    part_of mitochondrial large ribosomal subunit NAS
    Non-traceable Author Statement
    more info
    PubMed 
    located_in mitochondrion HDA PubMed 
    located_in mitochondrion ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    large ribosomal subunit protein bL21m
    Names
    39S ribosomal protein L21, mitochondrial

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001347420.2NP_001334349.1  large ribosomal subunit protein bL21m isoform 2

      Status: VALIDATED

      Source sequence(s)
      AL626765, AW050299, BC028768
      Consensus CDS
      CCDS84406.1
      UniProtKB/Swiss-Prot
      Q9CSH9, Q9D1N9, Q9D214
      Related
      ENSMUSP00000025743.7, ENSMUST00000025743.7
    2. NM_172252.4NP_758456.2  large ribosomal subunit protein bL21m isoform 1

      See identical proteins and their annotated locations for NP_758456.2

      Status: VALIDATED

      Source sequence(s)
      AK020739, BY273639
      Consensus CDS
      CCDS29394.1
      UniProtKB/Swiss-Prot
      Q9D1N9
      Related
      ENSMUSP00000025745.4, ENSMUST00000025745.10
      Conserved Domains (1) summary
      pfam00829
      Location:106182
      Ribosomal_L21p; Ribosomal prokaryotic L21 protein

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000085.7 Reference GRCm39 C57BL/6J

      Range
      3332997..3342837
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006531778.5XP_006531841.1  large ribosomal subunit protein bL21m isoform X1