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    Tb10.6k15.1290 pre-mRNA splicing factor ATP-dependent RNA helicase, putative [ Trypanosoma brucei brucei TREU927 ]

    Gene ID: 3663031, updated on 29-Oct-2024

    Summary

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    Gene symbol
    Tb10.6k15.1290
    Gene description
    pre-mRNA splicing factor ATP-dependent RNA helicase, putative
    Locus tag
    Tb10.6k15.1290
    Gene type
    protein coding
    RNA name
    pre-mRNA splicing factor ATP-dependent RNA helicase, putative
    RefSeq status
    PROVISIONAL
    Organism
    Trypanosoma brucei brucei TREU927 (strain: 927/4 GUTat10.1, sub-species: brucei)
    Lineage
    Eukaryota; Discoba; Euglenozoa; Kinetoplastea; Metakinetoplastina; Trypanosomatida; Trypanosomatidae; Trypanosoma
    Orthologs
    all
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    Genomic context

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    See Tb10.6k15.1290 in Genome Data Viewer
    Location:
    chromosome: 10
    Exon count:
    1
    Sequence:
    Chromosome: 10; NC_007283.1 (2223505..2225574)

    Chromosome 10 - NC_007283.1Genomic Context describing neighboring genes Neighboring gene hypothetical protein Neighboring gene hypothetical protein Neighboring gene hypothetical protein Neighboring gene hypothetical protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_007283.1

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The genome of the African trypanosome Trypanosoma brucei. Berriman M, et al. Science, 2005 Jul 15. PMID 16020726
    2. Comparative genomics of trypanosomatid parasitic protozoa. El-Sayed NM, et al. Science, 2005 Jul 15. PMID 16020724
    3. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    4. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables RNA binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in positive regulation of transcription by RNA polymerase I IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in intracellular anatomical structure IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in nucleolus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    pre-mRNA splicing factor ATP-dependent RNA helicase, putative
    XP_823137.1
    • similar to SP:Q14562: ATP-dependent helicase DHX8 (RNA helicase HRH1) (DEAH-box protein 8). {Homo sapiens}

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_007283.1 Reference assembly

      Range
      2223505..2225574
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_818044.1 → XP_823137.1  pre-mRNA splicing factor ATP-dependent RNA helicase, putative [Trypanosoma brucei brucei TREU927]

      See identical proteins and their annotated locations for XP_823137.1

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      Q38A61
      Conserved Domains (6) summary
      smart00487
      Location:17 → 195
      DEXDc; DEAD-like helicases superfamily
      smart00847
      Location:412 → 494
      HA2; Helicase associated domain (HA2) Add an annotation
      COG0513
      Location:110 → 381
      SrmB; Superfamily II DNA and RNA helicase [Replication, recombination and repair]
      cd00046
      Location:30 → 169
      DEXDc; DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
      pfam00271
      Location:207 → 343
      Helicase_C; Helicase conserved C-terminal domain
      pfam07717
      Location:600 → 678
      OB_NTP_bind; Oligonucleotide/oligosaccharide-binding (OB)-fold
    Protein Accession Links
    GenPept Link UniProtKB Link
    EAN78309.1

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Molecular Biology Databases
    Research Materials