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    Vdup1 Vitamin D[[3]] up-regulated protein 1 [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 38023, updated on 9-Dec-2024

    Summary

    Official Symbol
    Vdup1provided by FlyBase
    Official Full Name
    Vitamin D[[3]] up-regulated protein 1provided by FlyBase
    Primary source
    FLYBASE:FBgn0035103
    Locus tag
    Dmel_CG7047
    See related
    AllianceGenome:FB:FBgn0035103
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG7047; Dmel\CG7047; dvdup1; TXNIP; vdup1; VDUP1
    Summary
    Predicted to enable ubiquitin protein ligase binding activity. Involved in cell redox homeostasis and negative regulation of removal of superoxide radicals. Located in cytoplasm and nucleus. Is expressed in several structures, including adult fat body; epidermis; germline cell; glial cell; and gut section. Orthologous to human ARRDC1 (arrestin domain containing 1). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
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    Genomic context

    See Vdup1 in Genome Data Viewer
    Location:
    61B2-61B2; 3-1 cM
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3L NT_037436.4 (176306..178963, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3L NT_037436.3 (176306..178963, complement)

    Chromosome 3L - NT_037436.4Genomic Context describing neighboring genes Neighboring gene p130CAS Neighboring gene long non-coding RNA:CR43151 Neighboring gene antisense RNA:CR45806 Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene MAP kinase-specific phosphatase Neighboring gene Mitochondrial carrier homolog 1

    Genomic regions, transcripts, and products

    Bibliography

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables ubiquitin protein ligase binding ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    Process Evidence Code Pubs
    involved_in cell redox homeostasis IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in negative regulation of removal of superoxide radicals IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in protein transport IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in cytoplasm IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in nucleus IDA
    Inferred from Direct Assay
    more info
    PubMed 

    General protein information

    Preferred Names
    vitamin D[[3]] up-regulated protein 1
    Names
    CG7047-PA
    CG7047-PB
    CG7047-PC
    CG7047-PD
    CG7047-PE
    Vdup1-PA
    Vdup1-PB
    Vdup1-PC
    Vdup1-PD
    Vdup1-PE
    vitamin D3 up-regulated protein 1
    vitamin-D[[3]] upregulated protein 1

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_037436.4 Reference assembly

      Range
      176306..178963 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001169832.2NP_001163303.1  vitamin D[[3]] up-regulated protein 1, isoform D [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001163303.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q0E8K8, Q8SYE1
      Conserved Domains (2) summary
      smart01017
      Location:171299
      Arrestin_C; Arrestin (or S-antigen), C-terminal domain
      cl22903
      Location:8145
      Arrestin_N; Arrestin (or S-antigen), N-terminal domain
    2. NM_001274255.1NP_001261184.1  vitamin D[[3]] up-regulated protein 1, isoform E [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001261184.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q0E8K8, Q8SYE1
      Conserved Domains (2) summary
      smart01017
      Location:171299
      Arrestin_C; Arrestin (or S-antigen), C-terminal domain
      cl22903
      Location:8145
      Arrestin_N; Arrestin (or S-antigen), N-terminal domain
    3. NM_138160.4NP_612004.2  vitamin D[[3]] up-regulated protein 1, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_612004.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q0E8K8, Q8SYE1
      Related
      FBpp0072433
      Conserved Domains (2) summary
      smart01017
      Location:171299
      Arrestin_C; Arrestin (or S-antigen), C-terminal domain
      cl22903
      Location:8145
      Arrestin_N; Arrestin (or S-antigen), N-terminal domain
    4. NM_167798.3NP_728479.1  vitamin D[[3]] up-regulated protein 1, isoform C [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_728479.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q0E8K8, Q8SYE1
      Related
      FBpp0072434
      Conserved Domains (2) summary
      smart01017
      Location:171299
      Arrestin_C; Arrestin (or S-antigen), C-terminal domain
      cl22903
      Location:8145
      Arrestin_N; Arrestin (or S-antigen), N-terminal domain
    5. NM_206221.3NP_995943.1  vitamin D[[3]] up-regulated protein 1, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_995943.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q0E8K8, Q8SYE1
      Conserved Domains (2) summary
      smart01017
      Location:171299
      Arrestin_C; Arrestin (or S-antigen), C-terminal domain
      cl22903
      Location:8145
      Arrestin_N; Arrestin (or S-antigen), N-terminal domain