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    ImpE2 Ecdysone-inducible gene E2 [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 38432, updated on 9-Dec-2024

    Summary

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    Official Symbol
    ImpE2provided by FlyBase
    Official Full Name
    Ecdysone-inducible gene E2provided by FlyBase
    Primary source
    FLYBASE:FBgn0001254
    Locus tag
    Dmel_CG1934
    See related
    AllianceGenome:FB:FBgn0001254
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG1934; Dmel\CG1934; Imp-E2; IMP-E2
    Summary
    Predicted to be involved in imaginal disc eversion. Located in cytoplasm and extracellular region. Is expressed in several structures, including antennal anlage; anterior endoderm; embryonic/larval midgut primordium; endoderm anlage; and gut section. [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
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    Genomic context

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    See ImpE2 in Genome Data Viewer
    Location:
    63E2-63E2; 3-8 cM
    Exon count:
    1
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3L NT_037436.4 (3510974..3512681, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3L NT_037436.3 (3510974..3512681, complement)

    Chromosome 3L - NT_037436.4Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene long non-coding RNA:CR45043 Neighboring gene Ecdysone-induced protein 63E Neighboring gene long non-coding RNA:CR45820

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The Drosophila IMP-E2 gene encodes an apically secreted protein expressed during imaginal disc morphogenesis. Paine-Saunders S, et al. Dev Biol, 1990 Aug. PMID 2115480
    2. Genes expressed during imaginal disc morphogenesis: IMP-E1, a gene associated with epithelial cell rearrangement. Natzle JE, et al. Dev Biol, 1988 Oct. PMID 2458289
    3. NovoSpaRc: flexible spatial reconstruction of single-cell gene expression with optimal transport. Moriel N, et al. Nat Protoc, 2021 Sep. PMID 34349282
    4. Isolation of genes active during hormone-induced morphogenesis in Drosophila imaginal discs. Natzle JE, et al. J Biol Chem, 1986 Apr 25. PMID 3007512
    5. The L63 gene is necessary for the ecdysone-induced 63E late puff and encodes CDK proteins required for Drosophila development. Stowers RS, et al. Dev Biol, 2000 May 1. PMID 10772789

    See all (62) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Process Evidence Code Pubs
    involved_in imaginal disc eversion TAS
    Traceable Author Statement
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in extracellular region IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in extrinsic component of membrane TAS
    Traceable Author Statement
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    Ecdysone-inducible gene E2
    Names
    CG1934-PA
    ImpE2-PA

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_037436.4 Reference assembly

      Range
      3510974..3512681 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_057232.5 → NP_476580.1  Ecdysone-inducible gene E2 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_476580.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      P29681, Q9VZN9
      Related
      FBpp0073000
      Conserved Domains (1) summary
      PTZ00121
      Location:34 → 195
      PTZ00121; MAEBL; Provisional
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P29681.1 P29681

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Chemical Information
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