Ceacam3 CEA cell adhesion molecule 3 [Mus musculus (house mouse)] - Gene

Summary

Official Symbol: Ceacam3provided by MGI
Official Full Name: CEA cell adhesion molecule 3provided by MGI
Primary source: MGI:MGI:3646296
See related: Ensembl:ENSMUSG00000053228 AllianceGenome:MGI:3646296
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Mus musculus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as: Psg24; cea12; EG384557
Summary: Predicted to be involved in T cell activation and immune response. Predicted to be located in apical plasma membrane and cytosol. Predicted to be active in external side of plasma membrane. Orthologous to human CEACAM7 (CEA cell adhesion molecule 7). [provided by Alliance of Genome Resources, Dec 2024]
Expression: Restricted expression toward placenta adult (RPKM 81.1) See more
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Genomic context

Location:: 7 A2; 7 9.15 cM

Exon count:: 7

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCm39 (GCF_000001635.27)	7	NC_000073.7 (16884122..16898891)
108.20200622	previous assembly	GRCm38.p6 (GCF_000001635.26)	7	NC_000073.6 (17150197..17164966)

Chromosome 7 - NC_000073.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Mouse ENCODE transcriptome data
Description: RNA profiling data sets generated by the Mouse ENCODE project.
BioProject: PRJNA66167
Publication: PMID 25409824
Analysis date: n/a

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics (MGI)

Endonuclease-mediated (2)

Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Markers

D7Jcs3 (e-PCR), detects polymorphism
- UniSTS:461968

Gene Ontology Provided by MGI

Function	Evidence Code	Pubs
enables molecular_function	ND No biological Data available more info

Process	Evidence Code	Pubs
involved_in T cell activation	IBA Inferred from Biological aspect of Ancestor more info
involved_in biological_process	ND No biological Data available more info
involved_in immune response	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
located_in apical plasma membrane	ISO Inferred from Sequence Orthology more info
is_active_in cellular_component	ND No biological Data available more info
located_in cytosol	ISO Inferred from Sequence Orthology more info
is_active_in external side of plasma membrane	IBA Inferred from Biological aspect of Ancestor more info
located_in plasma membrane	ISO Inferred from Sequence Orthology more info

General protein information

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Preferred Names: carcinoembryonic antigen-related cell adhesion molecule 3

Names: pregnancy-specific glycoprotein 24

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_054059.2 → NP_473400.1 carcinoembryonic antigen-related cell adhesion molecule 3 precursor

Status: VALIDATED

Source sequence(s)

AC152074

Consensus CDS

CCDS57499.1

UniProtKB/TrEMBL

E9Q6J4

Related

ENSMUSP00000104131.3, ENSMUST00000108491.8

Conserved Domains (3) summary

cd05774
Location:271 → 375

Ig_CEACAM_D1; First immunoglobulin (Ig)-like domain of carcinoembryonic antigen (CEA) related cell adhesion molecule (CEACAM)

smart00410
Location:624 → 703

IG_like; Immunoglobulin like

cl11960
Location:613 → 703

Ig; Immunoglobulin domain

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

NC_000073.7 Reference GRCm39 C57BL/6J

Range

16884122..16898891

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_006540149.4 → XP_006540212.1 carcinoembryonic antigen-related cell adhesion molecule 3 isoform X1

Conserved Domains (2) summary

cd05774
Location:151 → 255

Ig_CEACAM_D1; First immunoglobulin (Ig)-like domain of carcinoembryonic antigen (CEA) related cell adhesion molecule (CEACAM)

cl11960
Location:493 → 583

Ig; Immunoglobulin domain
XM_006540151.4 → XP_006540214.1 carcinoembryonic antigen-related cell adhesion molecule 3 isoform X3

Conserved Domains (2) summary

cd05774
Location:151 → 255

Ig_CEACAM_D1; First immunoglobulin (Ig)-like domain of carcinoembryonic antigen (CEA) related cell adhesion molecule (CEACAM)

cl11960
Location:271 → 316

Ig; Immunoglobulin domain
XM_006540150.4 → XP_006540213.1 carcinoembryonic antigen-related cell adhesion molecule 3 isoform X2

Conserved Domains (2) summary

cd05774
Location:197 → 301

Ig_CEACAM_D1; First immunoglobulin (Ig)-like domain of carcinoembryonic antigen (CEA) related cell adhesion molecule (CEACAM)

cl11960
Location:303 → 393

Ig; Immunoglobulin domain