U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination
    • Showing Current items.

    ventx2.2.L VENT homeobox 2, gene 2 L homeolog [ Xenopus laevis (African clawed frog) ]

    Gene ID: 394272, updated on 4-Jan-2025

    Summary

    Go to the top of the page Help
    Official Symbol
    ventx2.2.L
    Official Full Name
    VENT homeobox 2, gene 2 L homeolog
    Primary source
    Xenbase:XB-GENE-920534
    Locus tag
    XELAEV_18034615mg
    See related
    EnsemblRapid:ENSXLAG00005014418 AllianceGenome:Xenbase:XB-GENE-920534
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Xenopus laevis
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
    Also known as
    Xom; vox; vent2; xom-A; vent-2; xvent2; xvent-2; ventx2.2
    Summary
    Predicted to enable DNA binding activity and DNA-binding transcription factor activity, RNA polymerase II-specific. Predicted to act upstream of or within regulation of DNA-templated transcription and spinal cord motor neuron cell fate specification. Predicted to be located in nucleus. Is expressed in anatomical system and primary germ layer. [provided by Alliance of Genome Resources, Jan 2025]
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See ventx2.2.L in Genome Data Viewer
    Location:
    chromosome: 7L
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    101 current Xenopus_laevis_v10.1 (GCF_017654675.1) 7L NC_054383.1 (21777297..21779193)
    100 previous assembly Xenopus_laevis_v2 (GCF_001663975.1) 7L NC_030736.1 (21829663..21831559)

    Chromosome 7L - NC_054383.1Genomic Context describing neighboring genes Neighboring gene VENT homeobox 3, gene 2 L homeolog Neighboring gene VENT homeobox 1, gene 2 L homeolog Neighboring gene VENT homeobox 1 gene 1 L homeolog Neighboring gene VENT homeobox 2 gene 1 L homeolog

    Genomic regions, transcripts, and products

    Go to the top of the page Help

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Xom: a Xenopus homeobox gene that mediates the early effects of BMP-4. Ladher R, et al. Development, 1996 Aug. PMID 8756284
    2. Xom interacts with and stimulates transcriptional activity of LEF1/TCFs: implications for ventral cell fate determination during vertebrate embryogenesis. Gao H, et al. Cell Res, 2007 Apr. PMID 17404593
    3. Genetic and genomic tools for Xenopus research: The NIH Xenopus initiative. Klein SL, et al. Dev Dyn, 2002 Dec. PMID 12454917
    4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

    Go to the top of the page Help

    Homology

    Gene Ontology Provided by Xenbase

    Function Evidence Code Pubs
    enables DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables DNA-binding transcription factor activity, RNA polymerase II-specific IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within regulation of DNA-templated transcription IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within spinal cord motor neuron cell fate specification IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

    Go to the top of the page Help
    Preferred Names
    VENT homeobox 2, gene 2 L homeolog
    Names
    homeobox protein

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001087462.1 → NP_001080931.1  VENT homeobox 2, gene 2 L homeolog

      See identical proteins and their annotated locations for NP_001080931.1

      Status: PROVISIONAL

      Source sequence(s)
      X98454
      UniProtKB/TrEMBL
      Q91914, Q9DG85
      Related
      ENSXLAP00005042211.1, ENSXLAT00005043277.1
      Conserved Domains (1) summary
      pfam00046
      Location:178 → 230
      Homeobox; Homeobox domain

    RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 101 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Xenopus_laevis_v10.1 Primary Assembly

    Genomic

    1. NC_054383.1 Reference Xenopus_laevis_v10.1 Primary Assembly

      Range
      21777297..21779193
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Molecular Biology Databases
    Research Materials