SERPINE2 serpin family E member 2 [Sus scrofa (pig)] - Gene

Summary

Official Symbol: SERPINE2provided by VGNC
Official Full Name: serpin family E member 2provided by VGNC
Primary source: VGNC:VGNC:96484
See related: Ensembl:ENSSSCG00000016233
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Sus scrofa
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Suina; Suidae; Sus
Also known as: PN-1
Expression: Biased expression in ovary (RPKM 89.5), spleen (RPKM 27.1) and 4 other tissues See more
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 15

Exon count:: 8

Annotation release	Status	Assembly	Chr	Location
106	current	Sscrofa11.1 (GCF_000003025.6)	15	NC_010457.5 (125748383..125777788, complement)
105	previous assembly	Sscrofa10.2 (GCF_000003025.5)	15	NC_010457.4 (139183910..139249590, complement)

Chromosome 15 - NC_010457.5 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Transcriptome data used for gene annotation
Description: Nine kinds of tissues and a mixture of multiple tissues were sequenced for genome annotation
BioProject: PRJNA311523
Publication: PMID 27646534
Analysis date: Thu Dec 14 17:10:49 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables serine-type endopeptidase inhibitor activity	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in negative regulation of endopeptidase activity	IEA Inferred from Electronic Annotation more info	PubMed
involved_in negative regulation of plasminogen activation	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in extracellular space	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: glia-derived nexin

Names: nexin-1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_214287.1 → NP_999452.1 glia-derived nexin precursor

See identical proteins and their annotated locations for NP_999452.1

Status: PROVISIONAL

Source sequence(s)

AY059415

UniProtKB/TrEMBL

A0A4X1U5V7, A0A5K1UAD0, A0A8D1D3U6, F1SR62, Q8WNW8

Related

ENSSSCP00000017197.3, ENSSSCT00000017676.4

Conserved Domains (1) summary

cd02051
Location:21 → 397

PAI-1_nexin-1; Plasminogen activator inhibitor-1_like. Plasminogen activator inhibitor-1 (PAI-1) is the primary, fast-acting inhibitor of plasminogen activators. It is often bound to vitronectin, an abundant component of the extracellular matrix in many tissues. ...