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    LINC00200 long intergenic non-protein coding RNA 200 [ Homo sapiens (human) ]

    Gene ID: 399706, updated on 10-Dec-2024

    Summary

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    Official Symbol
    LINC00200provided by HGNC
    Official Full Name
    long intergenic non-protein coding RNA 200provided by HGNC
    Primary source
    HGNC:HGNC:30974
    See related
    Ensembl:ENSG00000229205 AllianceGenome:HGNC:30974
    Gene type
    ncRNA
    RefSeq status
    PREDICTED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    C10orf139; NCRNA00200
    Expression
    Low expression observed in reference dataset See more
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    Genomic context

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    See LINC00200 in Genome Data Viewer
    Location:
    10p15.3
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 10 NC_000010.11 (1159768..1164672)
    RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 10 NC_060934.1 (1156489..1161402)
    RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 10 NC_000010.10 (1205708..1210612)

    Chromosome 10 - NC_000010.11Genomic Context describing neighboring genes Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 2067 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 2898 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 2899 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr10:1130525-1131024 Neighboring gene MED14-independent group 3 enhancer GRCh37_chr10:1141578-1142777 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr10:1148139-1148671 Neighboring gene MED14-independent group 3 enhancer GRCh37_chr10:1155609-1156808 Neighboring gene isopentenyl-diphosphate delta isomerase 1 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr10:1163429-1163930 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr10:1166460-1167101 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr10:1167102-1167742 Neighboring gene WD repeat domain 37 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr10:1196487-1196986 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr10:1199503-1200004 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr10:1200005-1200504 Neighboring gene uncharacterized LOC105376344 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr10:1201744-1202634 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr10:1219106-1219608 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr10:1230396-1230996 Neighboring gene CDK7 strongly-dependent group 2 enhancer GRCh37_chr10:1234984-1236183 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr10:1237029-1237528 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr10:1256314-1256814 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr10:1258172-1258702 Neighboring gene adenosine deaminase RNA specific B2 (inactive) Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr10:1283673-1284184 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr10:1284185-1284695 Neighboring gene H3K27ac hESC enhancer GRCh37_chr10:1297166-1297666 Neighboring gene H3K27ac hESC enhancer GRCh37_chr10:1297667-1298167 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr10:1312697-1313582 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr10:1313583-1314467 Neighboring gene MPRA-validated peak840 silencer Neighboring gene H3K4me1 hESC enhancer GRCh37_chr10:1315089-1315589 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr10:1334566-1335464 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr10:1335779-1336688 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr10:1351707-1352350 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr10:1352351-1352995 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr10:1354285-1354928 Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr10:1352996-1353639 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr10:1354929-1355573 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr10:1386449-1387132 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 2901 Neighboring gene uncharacterized LOC105376342 Neighboring gene Sharpr-MPRA regulatory region 10920 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr10:1421674-1422378 Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr10:1422379-1423081 Neighboring gene NANOG hESC enhancer GRCh37_chr10:1423311-1423822 Neighboring gene uncharacterized LOC124902364 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr10:1449419-1450003 Neighboring gene MED14-independent group 3 enhancer GRCh37_chr10:1451683-1452882

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Tissue-specific circular RNA induction during human fetal development
    • Description: 35 human fetal samples from 6 tissues (3 - 7 replicates per tissue) collected between 10 and 20 weeks gestational time were sequenced using Illumina TruSeq Stranded Total RNA
    • BioProject: PRJNA270632
    • Publication: PMID 26076956
    • Analysis date: Mon Apr 2 22:54:59 2018

    Bibliography

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    Related articles in PubMed

    1. LINC00200 contributes to the chemoresistance to oxaliplatin of gastric cancer cells via regulating E2F1/RAD51 axis. Lin M, et al. Hum Cell, 2021 Jul. PMID 33822325
    2. Complete sequencing and characterization of 21,243 full-length human cDNAs. Ota T, et al. Nat Genet, 2004 Jan. PMID 14702039
    3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. LINC00200 contributes to the chemoresistance to oxaliplatin of gastric cancer cells via regulating E2F1/RAD51 axis.
      Title: LINC00200 contributes to the chemoresistance to oxaliplatin of gastric cancer cells via regulating E2F1/RAD51 axis.
    Submit: New GeneRIF Correction

    Phenotypes

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    Review eQTL and phenotype association data in this region using PheGenI

    Variation

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    See variants in ClinVar

    See studies and variants in dbVar

    See Variation Viewer (GRCh37.p13)

    See Variation Viewer (GRCh38)

    General gene information

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    Markers

    Potential readthrough

    Included gene: WDR37

    Clone Names

    • FLJ40354

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    RNA

    1. NR_015376.2 RNA Sequence

      Status: PREDICTED

      Source sequence(s)
      AK097673, AL607085, BC133038, BC133040
      Related
      ENST00000425630.2

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000010.11 Reference GRCh38.p14 Primary Assembly

      Range
      1159768..1164672
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060934.1 Alternate T2T-CHM13v2.0

      Range
      1156489..1161402
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Suppressed Reference Sequence(s)

    The following Reference Sequences have been suppressed. Explain

    1. NM_001010910.1: Suppressed sequence

      Description
      NM_001010910.1: This RefSeq was permanently suppressed because currently there is support for the transcript but not for the protein.
    Nucleotide Protein
    Heading Accession and Version

    Gene LinkOut

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