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    dnajc27 DnaJ (Hsp40) homolog, subfamily C, member 27 [ Danio rerio (zebrafish) ]

    Gene ID: 402784, updated on 9-Dec-2024

    Summary

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    Official Symbol
    dnajc27provided by ZNC
    Official Full Name
    DnaJ (Hsp40) homolog, subfamily C, member 27provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-081022-93
    See related
    Ensembl:ENSDARG00000070916 AllianceGenome:ZFIN:ZDB-GENE-081022-93
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    rbj; zgc:194263; zgc:194279
    Summary
    Predicted to enable GTPase activity. Predicted to be involved in intracellular protein transport. Predicted to be located in nucleus. Orthologous to human DNAJC27 (DnaJ heat shock protein family (Hsp40) member C27). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    human mouse all
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    Genomic context

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    See dnajc27 in Genome Data Viewer
    Location:
    chromosome: 17
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 17 NC_007128.7 (33296620..33307886)
    105 previous assembly GRCz10 (GCF_000002035.5) 17 NC_007128.6 (33344122..33353288)

    Chromosome 17 - NC_007128.7Genomic Context describing neighboring genes Neighboring gene proopiomelanocortin a Neighboring gene EFR3 homolog Ba (S. cerevisiae) Neighboring gene si:ch211-132f19.7 Neighboring gene xanthine dehydrogenase

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. RJLs: a new family of Ras-related GTP-binding proteins. Nepomuceno-Silva JL, et al. Gene, 2004 Mar 3. PMID 14980719
    2. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
    3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables GTP binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables GTPase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables GTPase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables nucleotide binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in intracellular protein transport IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    dnaJ homolog subfamily C member 27
    Names
    rab and DnaJ domain-containing protein
    NP_001007163.1
    XP_005158785.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001007162.2 → NP_001007163.1  dnaJ homolog subfamily C member 27

      See identical proteins and their annotated locations for NP_001007163.1

      Status: VALIDATED

      Source sequence(s)
      BC162873
      UniProtKB/Swiss-Prot
      Q6IMK3
      UniProtKB/TrEMBL
      B3DHR2
      Related
      ENSDARP00000127972.1, ENSDART00000154580.2
      Conserved Domains (3) summary
      cd06257
      Location:217 → 264
      DnaJ; DnaJ domain or J-domain. DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s, ...
      cd04119
      Location:17 → 184
      RJL; Rab GTPase family J-like (RabJ-like)
      smart00175
      Location:17 → 176
      RAB; Rab subfamily of small GTPases

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007128.7 Reference GRCz11 Primary Assembly

      Range
      33296620..33307886
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_005158728.5 → XP_005158785.1  dnaJ homolog subfamily C member 27 isoform X1

      UniProtKB/TrEMBL
      A0A8M2B552, E7FCB8
      Related
      ENSDARP00000109834.1, ENSDART00000123114.3
      Conserved Domains (3) summary
      cd06257
      Location:217 → 264
      DnaJ; DnaJ domain or J-domain. DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s, ...
      cd04119
      Location:17 → 184
      RJL; Rab GTPase family J-like (RabJ-like)
      smart00175
      Location:17 → 176
      RAB; Rab subfamily of small GTPases

    RNA

    1. XR_222434.5 RNA Sequence

    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q6IMK3.1 GenPept UniProtKB/Swiss-Prot:Q6IMK3

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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