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    Or10al5b olfactory receptor family 10 subfamily AL member 5B [ Rattus norvegicus (Norway rat) ]

    Gene ID: 406013, updated on 4-Jan-2025

    Summary

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    Official Symbol
    Or10al5bprovided by RGD
    Official Full Name
    olfactory receptor family 10 subfamily AL member 5Bprovided by RGD
    Primary source
    RGD:1333192
    See related
    AllianceGenome:RGD:1333192
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    Olfr122; Olr1696; Olr1701
    Summary
    Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008]
    Expression
    Restricted expression toward (RPKM 11.7) See more
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    Genomic context

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    See Or10al5b in Genome Data Viewer
    Location:
    20p12
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 20 NC_086038.1 (803673..816671, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 20 NC_051355.1 (798038..810925, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 20 NC_005119.4 (1098304..1110769, complement)

    Chromosome 20 - NC_086038.1Genomic Context describing neighboring genes Neighboring gene olfactory receptor family 10 subfamily AL member 4B Neighboring gene olfactory receptor family 10 subfamily AL member 27 Neighboring gene olfactory receptor family 2 subfamily G member 25 Neighboring gene olfactory receptor family 2 subfamily AY member 1, pseudogene 1 Neighboring gene olfactory receptor family 14 subfamily J member 3B

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. Genome sequence of the Brown Norway rat yields insights into mammalian evolution. Gibbs RA, et al. Nature, 2004 Apr 1. PMID 15057822
    2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables G protein-coupled receptor activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables olfactory receptor activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in G protein-coupled receptor signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in detection of chemical stimulus involved in sensory perception of smell IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    olfactory receptor Olr1701
    Names
    olfactory receptor 122
    olfactory receptor 1696
    olfactory receptor 1701
    olfactory receptor gene Olr1701

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001001114.1 → NP_001001114.1  olfactory receptor Olr1701

      See identical proteins and their annotated locations for NP_001001114.1

      Status: REVIEWED

      Source sequence(s)
      JAXUCZ010000020
      UniProtKB/TrEMBL
      A0A8I6GE03, E9PTU2
      Conserved Domains (2) summary
      pfam00001
      Location:47 → 296
      7tm_1; 7 transmembrane receptor (rhodopsin family)
      cl21561
      Location:39 → 314
      7tm_4; Olfactory receptor

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086038.1 Reference GRCr8

      Range
      803673..816671 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006255863.5 → XP_006255925.1  olfactory receptor Olr1701 isoform X1

      See identical proteins and their annotated locations for XP_006255925.1

      UniProtKB/TrEMBL
      A0A8I6A102, A0A8I6G8S3
      Conserved Domains (2) summary
      pfam00001
      Location:67 → 316
      7tm_1; 7 transmembrane receptor (rhodopsin family)
      cl21561
      Location:59 → 334
      7tm_4; Olfactory receptor

    2. XM_006255861.5 → XP_006255923.1  olfactory receptor Olr1701 isoform X1

      See identical proteins and their annotated locations for XP_006255923.1

      UniProtKB/TrEMBL
      A0A8I6A102, A0A8I6G8S3
      Conserved Domains (2) summary
      pfam00001
      Location:67 → 316
      7tm_1; 7 transmembrane receptor (rhodopsin family)
      cl21561
      Location:59 → 334
      7tm_4; Olfactory receptor

    3. XM_063279335.1 → XP_063135405.1  olfactory receptor Olr1701 isoform X1

      UniProtKB/TrEMBL
      A0A8I6A102, A0A8I6G8S3

    4. XM_063279336.1 → XP_063135406.1  olfactory receptor Olr1701 isoform X2

      UniProtKB/TrEMBL
      E9PTU2
    Nucleotide Protein Strain
    Heading Accession and Version

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