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    tex tex [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 40983, updated on 9-Dec-2024

    Summary

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    Official Symbol
    texprovided by FlyBase
    Official Full Name
    texprovided by FlyBase
    Primary source
    FLYBASE:FBgn0037569
    Locus tag
    Dmel_CG9615
    See related
    AllianceGenome:FB:FBgn0037569
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG9615; Dmel\CG9615; TEX1; Thoc3
    Summary
    Predicted to be involved in mRNA export from nucleus. Predicted to be part of THO complex part of transcription export complex. Is expressed in several structures, including amnioserosa; dorsal ectoderm; hindgut anlage; inclusive hindgut primordium; and trunk mesoderm. Orthologous to human THOC3 (THO complex subunit 3). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See tex in Genome Data Viewer
    Location:
    84F10-84F11; 3-48 cM
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (8307473..8308645, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (4133195..4134367, complement)

    Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene mitochondrial ribosomal protein L1 Neighboring gene neuronally altered carbohydrate Neighboring gene suppressor-of-G2-allele-of-skp1 Neighboring gene mir-4918 stem loop Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Splicing-independent loading of TREX on nascent RNA is required for efficient expression of dual-strand piRNA clusters in Drosophila. Hur JK, et al. Genes Dev, 2016 Apr 1. PMID 27036967, Free PMC Article
    2. mRNA export and the TREX complex. Katahira J. Biochim Biophys Acta, 2012 Jun. PMID 22178508
    3. A length-dependent evolutionarily conserved pathway controls nuclear export of circular RNAs. Huang C, et al. Genes Dev, 2018 May 1. PMID 29773557, Free PMC Article
    4. Computational and experimental identification of mirtrons in Drosophila melanogaster and Caenorhabditis elegans. Chung WJ, et al. Genome Res, 2011 Feb. PMID 21177960, Free PMC Article
    5. Genome-wide analysis of mRNAs regulated by the THO complex in Drosophila melanogaster. Rehwinkel J, et al. Nat Struct Mol Biol, 2004 Jun. PMID 15133499

    See all (31) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Process Evidence Code Pubs
    involved_in mRNA export from nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in mRNA export from nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    part_of THO complex part of transcription export complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of transcription export complex ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  

    General protein information

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    Preferred Names
    tex
    Names
    CG9615-PA
    tex-PA

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033777.3 Reference assembly

      Range
      8307473..8308645 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_141527.3 → NP_649784.1  tex [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_649784.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q8MSF3, Q9VHT2
      Related
      FBpp0081350
      Conserved Domains (2) summary
      sd00039
      Location:32 → 70
      7WD40; WD40 repeat [structural motif]
      cl29593
      Location:19 → 263
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8MSF3 Q8MSF3
    Q9VHT2 Q9VHT2

    Gene LinkOut

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