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    Art6 Arginine methyltransferase 6 [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 41699, updated on 9-Dec-2024

    Summary

    Official Symbol
    Art6provided by FlyBase
    Official Full Name
    Arginine methyltransferase 6provided by FlyBase
    Primary source
    FLYBASE:FBgn0038189
    Locus tag
    Dmel_CG9927
    See related
    AllianceGenome:FB:FBgn0038189
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG9927; DART6; Dmel\CG9927
    Summary
    Predicted to enable histone methyltransferase activity; protein-arginine omega-N asymmetric methyltransferase activity; and protein-arginine omega-N monomethyltransferase activity. Predicted to be involved in chromatin remodeling and regulation of DNA-templated transcription. Predicted to be active in nucleus. Is expressed in organism and ovary. [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
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    Genomic context

    See Art6 in Genome Data Viewer
    Location:
    88A2-88A2; 3-54 cM
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (13944654..13945812, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (9770376..9771534, complement)

    Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene empty spiracles Neighboring gene Arginine methyltransferase 9 Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene Inositol polyphosphate 1-phosphatase

    Genomic regions, transcripts, and products

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables histone methyltransferase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables protein-arginine N-methyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables protein-arginine omega-N asymmetric methyltransferase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables protein-arginine omega-N monomethyltransferase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables protein-arginine omega-N monomethyltransferase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    Process Evidence Code Pubs
    involved_in chromatin remodeling IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in peptidyl-arginine methylation IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in regulation of DNA-templated transcription IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in nucleus ISS
    Inferred from Sequence or Structural Similarity
    more info
     

    General protein information

    Preferred Names
    arginine methyltransferase 6
    Names
    Art6-PA
    CG9927-PA
    NP_650322.1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033777.3 Reference assembly

      Range
      13944654..13945812 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_142065.2NP_650322.1  arginine methyltransferase 6 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_650322.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VFP8
      Related
      FBpp0082341
      Conserved Domains (1) summary
      cl17173
      Location:29161
      AdoMet_MTases; S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy). ...