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    Syp Syncrip [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 42460, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Sypprovided by FlyBase
    Official Full Name
    Syncripprovided by FlyBase
    Primary source
    FLYBASE:FBgn0038826
    Locus tag
    Dmel_CG17838
    See related
    AllianceGenome:FB:FBgn0038826
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    AI945337; anon-WO0118547.613; cg17838; CG17838; Dmel\CG17838; l(3)03806; syp
    Summary
    Enables lncRNA binding activity; mRNA 3'-UTR binding activity; and mRNA 5'-UTR binding activity. Involved in several processes, including dorsal appendage formation; negative regulation of synaptic assembly at neuromuscular junction; and post-transcriptional regulation of gene expression. Located in several cellular components, including basal cortex; postsynapse of neuromuscular junction; and ribonucleoprotein granule. Part of precatalytic spliceosome. Is expressed in several structures, including adult head; adult heart; esophagus primordium; foregut primordium; and gonad. Orthologous to human HNRNPR (heterogeneous nuclear ribonucleoprotein R) and SYNCRIP (synaptotagmin binding cytoplasmic RNA interacting protein). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See Syp in Genome Data Viewer
    Location:
    92F12-93A1; 3-69 cM
    Exon count:
    19
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (20756729..20810726)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (16582451..16636448)

    Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene Proteasome alpha4 subunit, Testis-specific 1 Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene Tak1-like 1 Neighboring gene Fancd2 Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. RNA-binding protein syncrip regulates starvation-induced hyperactivity in adult Drosophila. Chi W, et al. PLoS Genet, 2021 Feb. PMID 33617535, Free PMC Article
    2. Imp is expressed in INPs and newborn neurons where it regulates neuropil targeting in the central complex. Munroe JA, et al. Neural Dev, 2023 Nov 29. PMID 38031099, Free PMC Article
    3. A cryptic RNA-binding domain mediates Syncrip recognition and exosomal partitioning of miRNA targets. Hobor F, et al. Nat Commun, 2018 Feb 26. PMID 29483512, Free PMC Article
    4. Imp is required for timely exit from quiescence in Drosophila type II neuroblasts. Munroe JA, et al. PLoS One, 2022. PMID 36520944, Free PMC Article
    5. Mamo decodes hierarchical temporal gradients into terminal neuronal fate. Liu LY, et al. Elife, 2019 Sep 23. PMID 31545163, Free PMC Article

    See all (115) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. RNA-binding protein syncrip regulates starvation-induced hyperactivity in adult Drosophila.
      Title: RNA-binding protein syncrip regulates starvation-induced hyperactivity in adult Drosophila.
    2. Syncrip/hnRNP Q is required for activity-induced Msp300/Nesprin-1 expression and new synapse formation.
      Title: Syncrip/hnRNP Q is required for activity-induced Msp300/Nesprin-1 expression and new synapse formation.
    3. A cryptic RNA-binding domain mediates Syncrip recognition and exosomal partitioning of miRNA targets.
      Title: A cryptic RNA-binding domain mediates Syncrip recognition and exosomal partitioning of miRNA targets.
    4. the levels of Imp and Syp RNA-binding proteins regulate neuroblasts decommissioning.
      Title: Imp and Syp RNA-binding proteins govern decommissioning of Drosophila neural stem cells.
    5. the opposing Imp/Syp gradients encode stem cell age, specifying multiple cell fates within a lineage.
      Title: Opposing intrinsic temporal gradients guide neural stem cell production of varied neuronal fates.
    Submit: New GeneRIF Correction

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables RNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables lncRNA binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables mRNA 3'-UTR binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables mRNA 5'-UTR binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables mRNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables mRNA binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in dorsal appendage formation IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in mRNA splicing, via spliceosome IC
    Inferred by Curator
    more info
    		 PubMed 
    involved_in mRNA stabilization IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in negative regulation of synaptic assembly at neuromuscular junction IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in oocyte dorsal/ventral axis specification IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in regulation of neuromuscular synaptic transmission IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in regulation of oskar mRNA translation IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in basal cortex IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in cytosol IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in nucleus IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in postsynapse of neuromuscular junction IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    part_of precatalytic spliceosome HDA PubMed 
    part_of ribonucleoprotein complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in ribonucleoprotein granule IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    syncrip
    Names
    CG17838-PA
    CG17838-PB
    CG17838-PC
    CG17838-PD
    CG17838-PE
    CG17838-PF
    CG17838-PH
    CG17838-PI
    CG17838-PJ
    CG17838-PK
    CG17838-PL
    CG17838-PM
    CG17838-PN
    CG17838-PO
    CG17838-PP
    CG17838-PQ
    CG17838-PR
    CG17838-PS
    CG17838-PT
    CG17838-PV
    Syp-PA
    Syp-PB
    Syp-PC
    Syp-PD
    Syp-PE
    Syp-PF
    Syp-PH
    Syp-PI
    Syp-PJ
    Syp-PK
    Syp-PL
    Syp-PM
    Syp-PN
    Syp-PO
    Syp-PP
    Syp-PQ
    Syp-PR
    Syp-PS
    Syp-PT
    Syp-PV

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033777.3 Reference assembly

      Range
      20756729..20810726
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001275849.1 → NP_001262778.1  syncrip, isoform K [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001262778.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A0B4KHH8, Q86NT3
      Conserved Domains (3) summary
      cd12249
      Location:197 → 275
      RRM1_hnRNPR_like; RNA recognition motif 1 in heterogeneous nuclear ribonucleoprotein R (hnRNP R) and similar proteins
      cd12250
      Location:278 → 359
      RRM2_hnRNPR_like; RNA recognition motif 2 in heterogeneous nuclear ribonucleoprotein R (hnRNP R) and similar proteins
      cd12251
      Location:373 → 444
      RRM3_hnRNPR_like; RNA recognition motif 3 in heterogeneous nuclear ribonucleoprotein R (hnRNP R) and similar proteins

    2. NM_169927.3 → NP_732557.2  syncrip, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_732557.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q8IN47
      Related
      FBpp0083365
      Conserved Domains (3) summary
      cd12249
      Location:197 → 275
      RRM1_hnRNPR_like; RNA recognition motif 1 in heterogeneous nuclear ribonucleoprotein R (hnRNP R) and similar proteins
      cd12250
      Location:278 → 359
      RRM2_hnRNPR_like; RNA recognition motif 2 in heterogeneous nuclear ribonucleoprotein R (hnRNP R) and similar proteins
      cd12251
      Location:373 → 444
      RRM3_hnRNPR_like; RNA recognition motif 3 in heterogeneous nuclear ribonucleoprotein R (hnRNP R) and similar proteins

    3. NM_001104379.2 → NP_001097849.1  syncrip, isoform H [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001097849.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A8JR54
      Conserved Domains (3) summary
      cd12249
      Location:168 → 246
      RRM1_hnRNPR_like; RNA recognition motif 1 in heterogeneous nuclear ribonucleoprotein R (hnRNP R) and similar proteins
      cd12250
      Location:249 → 330
      RRM2_hnRNPR_like; RNA recognition motif 2 in heterogeneous nuclear ribonucleoprotein R (hnRNP R) and similar proteins
      cd12251
      Location:344 → 415
      RRM3_hnRNPR_like; RNA recognition motif 3 in heterogeneous nuclear ribonucleoprotein R (hnRNP R) and similar proteins

    4. NM_001369986.1 → NP_001356920.1  syncrip, isoform S [Drosophila melanogaster]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A4D6K4U6, Q86NT3
      Conserved Domains (1) summary
      TIGR01648
      Location:145 → 547
      hnRNP-R-Q; heterogeneous nuclear ribonucleoprotein R, Q family

    5. NM_001369987.1 → NP_001356921.1  syncrip, isoform T [Drosophila melanogaster]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A4D6K1Z7
      Conserved Domains (1) summary
      TIGR01648
      Location:145 → 547
      hnRNP-R-Q; heterogeneous nuclear ribonucleoprotein R, Q family

    6. NM_001275847.1 → NP_001262776.1  syncrip, isoform I [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001262776.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A0B4KH21
      Conserved Domains (3) summary
      cd12249
      Location:197 → 275
      RRM1_hnRNPR_like; RNA recognition motif 1 in heterogeneous nuclear ribonucleoprotein R (hnRNP R) and similar proteins
      cd12250
      Location:278 → 359
      RRM2_hnRNPR_like; RNA recognition motif 2 in heterogeneous nuclear ribonucleoprotein R (hnRNP R) and similar proteins
      cd12251
      Location:373 → 444
      RRM3_hnRNPR_like; RNA recognition motif 3 in heterogeneous nuclear ribonucleoprotein R (hnRNP R) and similar proteins

    7. NM_001275850.1 → NP_001262779.1  syncrip, isoform M [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001262779.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A0B4KGK5, Q86NT3
      Conserved Domains (3) summary
      cd12249
      Location:197 → 275
      RRM1_hnRNPR_like; RNA recognition motif 1 in heterogeneous nuclear ribonucleoprotein R (hnRNP R) and similar proteins
      cd12250
      Location:278 → 359
      RRM2_hnRNPR_like; RNA recognition motif 2 in heterogeneous nuclear ribonucleoprotein R (hnRNP R) and similar proteins
      cd12251
      Location:373 → 444
      RRM3_hnRNPR_like; RNA recognition motif 3 in heterogeneous nuclear ribonucleoprotein R (hnRNP R) and similar proteins

    8. NM_142656.4 → NP_650913.2  syncrip, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_650913.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      A8JR56, Q7KSA0, Q86NT3
      Conserved Domains (3) summary
      cd12249
      Location:163 → 241
      RRM1_hnRNPR_like; RNA recognition motif 1 in heterogeneous nuclear ribonucleoprotein R (hnRNP R) and similar proteins
      cd12250
      Location:244 → 325
      RRM2_hnRNPR_like; RNA recognition motif 2 in heterogeneous nuclear ribonucleoprotein R (hnRNP R) and similar proteins
      cd12251
      Location:339 → 410
      RRM3_hnRNPR_like; RNA recognition motif 3 in heterogeneous nuclear ribonucleoprotein R (hnRNP R) and similar proteins

    9. NM_001275851.1 → NP_001262780.1  syncrip, isoform N [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001262780.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A0B4KGF9, Q86NT3
      Conserved Domains (3) summary
      cd12249
      Location:163 → 241
      RRM1_hnRNPR_like; RNA recognition motif 1 in heterogeneous nuclear ribonucleoprotein R (hnRNP R) and similar proteins
      cd12250
      Location:244 → 325
      RRM2_hnRNPR_like; RNA recognition motif 2 in heterogeneous nuclear ribonucleoprotein R (hnRNP R) and similar proteins
      cd12251
      Location:339 → 410
      RRM3_hnRNPR_like; RNA recognition motif 3 in heterogeneous nuclear ribonucleoprotein R (hnRNP R) and similar proteins

    10. NM_001275855.1 → NP_001262784.1  syncrip, isoform R [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001262784.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A0B4KGK8
      Conserved Domains (3) summary
      cd12249
      Location:163 → 241
      RRM1_hnRNPR_like; RNA recognition motif 1 in heterogeneous nuclear ribonucleoprotein R (hnRNP R) and similar proteins
      cd12250
      Location:244 → 325
      RRM2_hnRNPR_like; RNA recognition motif 2 in heterogeneous nuclear ribonucleoprotein R (hnRNP R) and similar proteins
      cd12251
      Location:339 → 410
      RRM3_hnRNPR_like; RNA recognition motif 3 in heterogeneous nuclear ribonucleoprotein R (hnRNP R) and similar proteins

    11. NM_169928.3 → NP_732558.2  syncrip, isoform C [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_732558.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q7KSA1, Q95TW4
      Conserved Domains (3) summary
      cd12249
      Location:163 → 241
      RRM1_hnRNPR_like; RNA recognition motif 1 in heterogeneous nuclear ribonucleoprotein R (hnRNP R) and similar proteins
      cd12250
      Location:244 → 325
      RRM2_hnRNPR_like; RNA recognition motif 2 in heterogeneous nuclear ribonucleoprotein R (hnRNP R) and similar proteins
      cd12251
      Location:339 → 410
      RRM3_hnRNPR_like; RNA recognition motif 3 in heterogeneous nuclear ribonucleoprotein R (hnRNP R) and similar proteins

    12. NM_169929.3 → NP_732559.1  syncrip, isoform F [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_732559.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A4V364
      Related
      FBpp0083368
      Conserved Domains (3) summary
      cd12249
      Location:163 → 241
      RRM1_hnRNPR_like; RNA recognition motif 1 in heterogeneous nuclear ribonucleoprotein R (hnRNP R) and similar proteins
      cd12250
      Location:244 → 325
      RRM2_hnRNPR_like; RNA recognition motif 2 in heterogeneous nuclear ribonucleoprotein R (hnRNP R) and similar proteins
      cd12251
      Location:339 → 410
      RRM3_hnRNPR_like; RNA recognition motif 3 in heterogeneous nuclear ribonucleoprotein R (hnRNP R) and similar proteins

    13. NM_001104378.2 → NP_001097848.2  syncrip, isoform L [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001097848.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      A8JR56, Q7KSA0, Q86NT3
      Conserved Domains (3) summary
      cd12249
      Location:163 → 241
      RRM1_hnRNPR_like; RNA recognition motif 1 in heterogeneous nuclear ribonucleoprotein R (hnRNP R) and similar proteins
      cd12250
      Location:244 → 325
      RRM2_hnRNPR_like; RNA recognition motif 2 in heterogeneous nuclear ribonucleoprotein R (hnRNP R) and similar proteins
      cd12251
      Location:339 → 410
      RRM3_hnRNPR_like; RNA recognition motif 3 in heterogeneous nuclear ribonucleoprotein R (hnRNP R) and similar proteins

    14. NM_001275853.1 → NP_001262782.1  syncrip, isoform P [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001262782.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A0B4KGF9, Q86NT3
      Conserved Domains (3) summary
      cd12249
      Location:163 → 241
      RRM1_hnRNPR_like; RNA recognition motif 1 in heterogeneous nuclear ribonucleoprotein R (hnRNP R) and similar proteins
      cd12250
      Location:244 → 325
      RRM2_hnRNPR_like; RNA recognition motif 2 in heterogeneous nuclear ribonucleoprotein R (hnRNP R) and similar proteins
      cd12251
      Location:339 → 410
      RRM3_hnRNPR_like; RNA recognition motif 3 in heterogeneous nuclear ribonucleoprotein R (hnRNP R) and similar proteins

    15. NM_169925.3 → NP_732555.1  syncrip, isoform E [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_732555.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      C6SV30, Q8IN48
      Related
      FBpp0083370
      Conserved Domains (2) summary
      TIGR01648
      Location:153 → 508
      hnRNP-R-Q; heterogeneous nuclear ribonucleoprotein R, Q family
      cd21065
      Location:68 → 150
      NURR_Syncrip-like; NURR (N-terminal unit for RNA recognition) domain found in Drosophila melanogaster Syncrip and similar proteins

    16. NM_001275854.1 → NP_001262783.1  syncrip, isoform Q [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001262783.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A0B4KHI4, Q86NT3
      Conserved Domains (3) summary
      cd12249
      Location:205 → 283
      RRM1_hnRNPR_like; RNA recognition motif 1 in heterogeneous nuclear ribonucleoprotein R (hnRNP R) and similar proteins
      cd12250
      Location:286 → 367
      RRM2_hnRNPR_like; RNA recognition motif 2 in heterogeneous nuclear ribonucleoprotein R (hnRNP R) and similar proteins
      cd12251
      Location:381 → 452
      RRM3_hnRNPR_like; RNA recognition motif 3 in heterogeneous nuclear ribonucleoprotein R (hnRNP R) and similar proteins

    17. NM_001275848.1 → NP_001262777.1  syncrip, isoform J [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001262777.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A0B4KHT5, Q86NT3
      Conserved Domains (3) summary
      cd12249
      Location:205 → 283
      RRM1_hnRNPR_like; RNA recognition motif 1 in heterogeneous nuclear ribonucleoprotein R (hnRNP R) and similar proteins
      cd12250
      Location:286 → 367
      RRM2_hnRNPR_like; RNA recognition motif 2 in heterogeneous nuclear ribonucleoprotein R (hnRNP R) and similar proteins
      cd12251
      Location:381 → 452
      RRM3_hnRNPR_like; RNA recognition motif 3 in heterogeneous nuclear ribonucleoprotein R (hnRNP R) and similar proteins

    18. NM_169926.2 → NP_732556.1  syncrip, isoform D [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_732556.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q86NT3, Q9VDI8
      Related
      FBpp0083369
      Conserved Domains (3) summary
      cd12249
      Location:205 → 283
      RRM1_hnRNPR_like; RNA recognition motif 1 in heterogeneous nuclear ribonucleoprotein R (hnRNP R) and similar proteins
      cd12250
      Location:286 → 367
      RRM2_hnRNPR_like; RNA recognition motif 2 in heterogeneous nuclear ribonucleoprotein R (hnRNP R) and similar proteins
      cd12251
      Location:381 → 452
      RRM3_hnRNPR_like; RNA recognition motif 3 in heterogeneous nuclear ribonucleoprotein R (hnRNP R) and similar proteins

    19. NM_001369988.1 → NP_001356922.1  syncrip, isoform V [Drosophila melanogaster]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A4D6K3P4
      Conserved Domains (1) summary
      TIGR01648
      Location:153 → 555
      hnRNP-R-Q; heterogeneous nuclear ribonucleoprotein R, Q family

    20. NM_001275852.1 → NP_001262781.1  syncrip, isoform O [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001262781.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A0B4KH24
      Conserved Domains (3) summary
      cd12249
      Location:205 → 283
      RRM1_hnRNPR_like; RNA recognition motif 1 in heterogeneous nuclear ribonucleoprotein R (hnRNP R) and similar proteins
      cd12250
      Location:286 → 367
      RRM2_hnRNPR_like; RNA recognition motif 2 in heterogeneous nuclear ribonucleoprotein R (hnRNP R) and similar proteins
      cd12251
      Location:381 → 452
      RRM3_hnRNPR_like; RNA recognition motif 3 in heterogeneous nuclear ribonucleoprotein R (hnRNP R) and similar proteins
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    A0A0B4KGF9 A0A0B4KGF9
    A0A0B4KGK5 A0A0B4KGK5
    A0A0B4KGK8 A0A0B4KGK8
    A0A0B4KH21 A0A0B4KH21
    A0A0B4KH24 A0A0B4KH24
    A0A0B4KHH8 A0A0B4KHH8
    A0A0B4KHI4 A0A0B4KHI4
    A0A0B4KHT5 A0A0B4KHT5
    A0A4D6K1Z7 A0A4D6K1Z7
    A0A4D6K3P4 A0A4D6K3P4
    A0A4D6K4U6 A0A4D6K4U6
    A4V364 A4V364
    A8JR54 A8JR54
    Q5U0U3 Q5U0U3
    Q7KSA0 Q7KSA0
    Q86NT3 Q86NT3
    Q8IN47 Q8IN47
    Q8IN48 Q8IN48
    Q95TW4 Q95TW4
    Q9VDI8 Q9VDI8

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