faf2.S Fas associated factor family member 2 S homeolog [Xenopus laevis (African clawed frog)] - Gene

Summary

Official Symbol: faf2.S
Official Full Name: Fas associated factor family member 2 S homeolog
Primary source: Xenbase:XB-GENE-6254585
Locus tag: XELAEV_18021354mg
See related: EnsemblRapid:ENSXLAG00005015672 AllianceGenome:Xenbase:XB-GENE-6254585
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Xenopus laevis
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
Also known as: etea; faf2; ubxd8; faf2-a; faf2-b; ubxn3b; ubxd8-a
Summary: Predicted to enable protein-macromolecule adaptor activity. Predicted to act upstream of or within stress granule disassembly. Predicted to be located in cytoplasm and lipid droplet. Predicted to be active in endoplasmic reticulum. Orthologous to human FAF2 (Fas associated factor family member 2). [provided by Alliance of Genome Resources, Jan 2025]
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Genomic context

Location:: chromosome: 3S

Exon count:: 11

Annotation release	Status	Assembly	Chr	Location
101	current	Xenopus_laevis_v10.1 (GCF_017654675.1)	3S	NC_054376.1 (99556141..99567643)
100	previous assembly	Xenopus_laevis_v2 (GCF_001663975.1)	3S	NC_030729.1 (97691340..97702842)

Chromosome 3S - NC_054376.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by Xenbase

Function	Evidence Code	Pubs
enables protein-macromolecule adaptor activity	ISS Inferred from Sequence or Structural Similarity more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within stress granule disassembly	ISS Inferred from Sequence or Structural Similarity more info

Component	Evidence Code	Pubs
located_in cytoplasm	IEA Inferred from Electronic Annotation more info
located_in endoplasmic reticulum	IEA Inferred from Electronic Annotation more info
is_active_in endoplasmic reticulum	ISS Inferred from Sequence or Structural Similarity more info
located_in lipid droplet	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: FAS-associated factor 2-A

Names: UBX domain-containing protein 8-A

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001093644.1 → NP_001087113.1 FAS-associated factor 2-A

See identical proteins and their annotated locations for NP_001087113.1

Status: PROVISIONAL

Source sequence(s)

BC078001

UniProtKB/Swiss-Prot

Q6AZH6

UniProtKB/TrEMBL

A0A974DBK2

Related

ENSXLAP00005046127.1, ENSXLAT00005047226.1

Conserved Domains (3) summary

cd01774
Location:358 → 442

Faf1_like2_UBX; Faf1 ike-2 UBX domain

cd02991
Location:154 → 269

UAS_ETEA; UAS family, ETEA subfamily; composed of proteins similar to human ETEA protein, the translation product of a highly expressed gene in the T-cells and eosinophils of atopic dermatitis patients compared with those of normal individuals. ETEA shows homology ...

cd14414
Location:15 → 52

UBA_FAF2; UBA-like TAP-C domain found in FAS-associated factor 2 (FAF2) and similar proteins