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    PNPLA7 patatin like phospholipase domain containing 7 [ Canis lupus familiaris (dog) ]

    Gene ID: 480663, updated on 17-Aug-2024

    Summary

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    Official Symbol
    PNPLA7provided by VGNC
    Official Full Name
    patatin like phospholipase domain containing 7provided by VGNC
    Primary source
    VGNC:VGNC:44757
    See related
    Ensembl:ENSCAFG00845021517
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Canis lupus familiaris (sub-species: familiaris)
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
    Orthologs
    human mouse all
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    Genomic context

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    See PNPLA7 in Genome Data Viewer
    Location:
    chromosome: 9
    Exon count:
    37
    Annotation release Status Assembly Chr Location
    106 current ROS_Cfam_1.0 (GCF_014441545.1) 9 NC_051813.1 (49083836..49148496)
    106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 9 NC_006591.4 (47408962..47473587)
    106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 9 NC_049230.1 (48205678..48270340)
    106 current UMICH_Zoey_3.1 (GCF_005444595.1) 9 NC_049269.1 (47860228..47924866)
    106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 9 NC_049750.1 (48159209..48223845)

    Chromosome 9 - NC_051813.1Genomic Context describing neighboring genes Neighboring gene diphthamide biosynthesis 7 Neighboring gene mitochondrial ribosomal protein L41 Neighboring gene NMDA receptor synaptonuclear signaling and neuronal migration factor Neighboring gene ectonucleoside triphosphate diphosphohydrolase 8

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables lysophospholipase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in lipid metabolic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in endoplasmic reticulum IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    patatin-like phospholipase domain-containing protein 7
    XP_005625095.1
    XP_022279214.1
    XP_022279215.1
    XP_038342654.1
    XP_038342655.1
    XP_038342656.1
    XP_038342657.1
    XP_038404520.1
    XP_038404521.1
    XP_038404522.1
    XP_038404523.1
    XP_038404524.1
    XP_038468461.1
    XP_038468462.1
    XP_038468463.1
    XP_038468464.1
    XP_038533739.1
    XP_038533740.1
    XP_038533741.1
    XP_038533742.1
    XP_537782.4

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ROS_Cfam_1.0

    Genomic

    1. NC_051813.1 Reference ROS_Cfam_1.0

      Range
      49083836..49148496
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038677813.1 → XP_038533741.1  patatin-like phospholipase domain-containing protein 7 isoform X3

      UniProtKB/TrEMBL
      A0A8I3P9L5, A0A8P0SNF6, A0A8P0TTB2
      Related
      ENSCAFP00845030258.1, ENSCAFT00845038643.1
      Conserved Domains (3) summary
      cd07225
      Location:936 → 1241
      Pat_PNPLA6_PNPLA7; Patatin-like phospholipase domain containing protein 6 and protein 7
      cd12087
      Location:29 → 66
      TM_EGFR-like; Transmembrane domain of the Epidermal Growth Factor Receptor family of Protein Tyrosine Kinases
      cd00038
      Location:607 → 715
      CAP_ED; effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO ...

    2. XM_038677814.1 → XP_038533742.1  patatin-like phospholipase domain-containing protein 7 isoform X4

      UniProtKB/TrEMBL
      A0A8I3P9L5, A0A8P0TTB2
      Conserved Domains (2) summary
      cd07225
      Location:902 → 1207
      Pat_PNPLA6_PNPLA7; Patatin-like phospholipase domain containing protein 6 and protein 7
      cd00038
      Location:573 → 681
      CAP_ED; effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO ...

    3. XM_038677811.1 → XP_038533739.1  patatin-like phospholipase domain-containing protein 7 isoform X1

      UniProtKB/TrEMBL
      A0A8I3P9L5, A0A8I3PH07, A0A8P0TTB2
      Related
      ENSCAFP00845029768.1, ENSCAFT00845037989.1
      Conserved Domains (3) summary
      cd07225
      Location:949 → 1254
      Pat_PNPLA6_PNPLA7; Patatin-like phospholipase domain containing protein 6 and protein 7
      cd12087
      Location:42 → 79
      TM_EGFR-like; Transmembrane domain of the Epidermal Growth Factor Receptor family of Protein Tyrosine Kinases
      cd00038
      Location:620 → 728
      CAP_ED; effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO ...

    4. XM_038677812.1 → XP_038533740.1  patatin-like phospholipase domain-containing protein 7 isoform X2

      UniProtKB/TrEMBL
      A0A8I3P9L5, A0A8P0TTB2
      Conserved Domains (3) summary
      cd07225
      Location:946 → 1251
      Pat_PNPLA6_PNPLA7; Patatin-like phospholipase domain containing protein 6 and protein 7
      cd12087
      Location:42 → 79
      TM_EGFR-like; Transmembrane domain of the Epidermal Growth Factor Receptor family of Protein Tyrosine Kinases
      cd00038
      Location:620 → 728
      CAP_ED; effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO ...

    Alternate UMICH_Zoey_3.1

    Genomic

    1. NC_049269.1 Alternate UMICH_Zoey_3.1

      Range
      47860228..47924866
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038486728.1 → XP_038342656.1  patatin-like phospholipase domain-containing protein 7 isoform X3

      Conserved Domains (3) summary
      cd07225
      Location:936 → 1241
      Pat_PNPLA6_PNPLA7; Patatin-like phospholipase domain containing protein 6 and protein 7
      cd12087
      Location:29 → 66
      TM_EGFR-like; Transmembrane domain of the Epidermal Growth Factor Receptor family of Protein Tyrosine Kinases
      cd00038
      Location:607 → 715
      CAP_ED; effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO ...

    2. XM_038486729.1 → XP_038342657.1  patatin-like phospholipase domain-containing protein 7 isoform X4

      Conserved Domains (2) summary
      cd07225
      Location:902 → 1207
      Pat_PNPLA6_PNPLA7; Patatin-like phospholipase domain containing protein 6 and protein 7
      cd00038
      Location:573 → 681
      CAP_ED; effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO ...

    3. XM_038486726.1 → XP_038342654.1  patatin-like phospholipase domain-containing protein 7 isoform X1

      Conserved Domains (3) summary
      cd07225
      Location:949 → 1254
      Pat_PNPLA6_PNPLA7; Patatin-like phospholipase domain containing protein 6 and protein 7
      cd12087
      Location:42 → 79
      TM_EGFR-like; Transmembrane domain of the Epidermal Growth Factor Receptor family of Protein Tyrosine Kinases
      cd00038
      Location:620 → 728
      CAP_ED; effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO ...

    4. XM_038486727.1 → XP_038342655.1  patatin-like phospholipase domain-containing protein 7 isoform X2

      Conserved Domains (3) summary
      cd07225
      Location:946 → 1251
      Pat_PNPLA6_PNPLA7; Patatin-like phospholipase domain containing protein 6 and protein 7
      cd12087
      Location:42 → 79
      TM_EGFR-like; Transmembrane domain of the Epidermal Growth Factor Receptor family of Protein Tyrosine Kinases
      cd00038
      Location:620 → 728
      CAP_ED; effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO ...

    Alternate UNSW_CanFamBas_1.0

    Genomic

    1. NC_049750.1 Alternate UNSW_CanFamBas_1.0

      Range
      48159209..48223845
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038612535.1 → XP_038468463.1  patatin-like phospholipase domain-containing protein 7 isoform X3

    2. XM_038612536.1 → XP_038468464.1  patatin-like phospholipase domain-containing protein 7 isoform X4

    3. XM_038612534.1 → XP_038468462.1  patatin-like phospholipase domain-containing protein 7 isoform X2

    4. XM_038612533.1 → XP_038468461.1  patatin-like phospholipase domain-containing protein 7 isoform X1

    Alternate UU_Cfam_GSD_1.0

    Genomic

    1. NC_049230.1 Alternate UU_Cfam_GSD_1.0

      Range
      48205678..48270340
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038548592.1 → XP_038404520.1  patatin-like phospholipase domain-containing protein 7 isoform X3

      UniProtKB/TrEMBL
      A0A8I3P9L5, A0A8P0SNF6, A0A8P0TTB2
      Conserved Domains (3) summary
      cd07225
      Location:936 → 1241
      Pat_PNPLA6_PNPLA7; Patatin-like phospholipase domain containing protein 6 and protein 7
      cd12087
      Location:29 → 66
      TM_EGFR-like; Transmembrane domain of the Epidermal Growth Factor Receptor family of Protein Tyrosine Kinases
      cd00038
      Location:607 → 715
      CAP_ED; effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO ...

    2. XM_038548594.1 → XP_038404522.1  patatin-like phospholipase domain-containing protein 7 isoform X5

      UniProtKB/TrEMBL
      A0A8I3P9L5, A0A8P0TTB2

    3. XM_038548595.1 → XP_038404523.1  patatin-like phospholipase domain-containing protein 7 isoform X4

      UniProtKB/TrEMBL
      A0A8I3P9L5, A0A8P0TTB2
      Conserved Domains (2) summary
      cd07225
      Location:902 → 1207
      Pat_PNPLA6_PNPLA7; Patatin-like phospholipase domain containing protein 6 and protein 7
      cd00038
      Location:573 → 681
      CAP_ED; effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO ...

    4. XM_038548593.1 → XP_038404521.1  patatin-like phospholipase domain-containing protein 7 isoform X3

      UniProtKB/TrEMBL
      A0A8I3P9L5, A0A8P0SNF6, A0A8P0TTB2
      Conserved Domains (3) summary
      cd07225
      Location:936 → 1241
      Pat_PNPLA6_PNPLA7; Patatin-like phospholipase domain containing protein 6 and protein 7
      cd12087
      Location:29 → 66
      TM_EGFR-like; Transmembrane domain of the Epidermal Growth Factor Receptor family of Protein Tyrosine Kinases
      cd00038
      Location:607 → 715
      CAP_ED; effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO ...

    5. XM_038548596.1 → XP_038404524.1  patatin-like phospholipase domain-containing protein 7 isoform X4

      UniProtKB/TrEMBL
      A0A8I3P9L5, A0A8P0TTB2
      Conserved Domains (2) summary
      cd07225
      Location:902 → 1207
      Pat_PNPLA6_PNPLA7; Patatin-like phospholipase domain containing protein 6 and protein 7
      cd00038
      Location:573 → 681
      CAP_ED; effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO ...

    Alternate Dog10K_Boxer_Tasha Primary Assembly

    Genomic

    1. NC_006591.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

      Range
      47408962..47473587
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_537782.7 → XP_537782.4  patatin-like phospholipase domain-containing protein 7 isoform X3

      UniProtKB/TrEMBL
      A0A8I3P9L5, A0A8P0SNF6, A0A8P0TTB2
      Conserved Domains (3) summary
      cd07225
      Location:936 → 1241
      Pat_PNPLA6_PNPLA7; Patatin-like phospholipase domain containing protein 6 and protein 7
      cd12087
      Location:29 → 66
      TM_EGFR-like; Transmembrane domain of the Epidermal Growth Factor Receptor family of Protein Tyrosine Kinases
      cd00038
      Location:607 → 715
      CAP_ED; effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO ...

    2. XM_022423507.2 → XP_022279215.1  patatin-like phospholipase domain-containing protein 7 isoform X4

      UniProtKB/TrEMBL
      A0A8I3P9L5, A0A8P0TTB2
      Conserved Domains (2) summary
      cd07225
      Location:902 → 1207
      Pat_PNPLA6_PNPLA7; Patatin-like phospholipase domain containing protein 6 and protein 7
      cd00038
      Location:573 → 681
      CAP_ED; effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO ...

    3. XM_005625038.4 → XP_005625095.1  patatin-like phospholipase domain-containing protein 7 isoform X1

      UniProtKB/TrEMBL
      A0A8I3P9L5, A0A8P0TTB2
      Conserved Domains (5) summary
      cd07225
      Location:949 → 1254
      Pat_PNPLA6_PNPLA7; Patatin-like phospholipase domain containing protein 6 and protein 7
      cd12087
      Location:42 → 79
      TM_EGFR-like; Transmembrane domain of the Epidermal Growth Factor Receptor family of Protein Tyrosine Kinases
      COG0664
      Location:177 → 319
      Crp; cAMP-binding domain of CRP or a regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]
      COG1752
      Location:954 → 1255
      RssA; Predicted acylesterase/phospholipase RssA, containd patatin domain [General function prediction only]
      cd00038
      Location:620 → 728
      CAP_ED; effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO ...

    4. XM_022423506.2 → XP_022279214.1  patatin-like phospholipase domain-containing protein 7 isoform X2

      UniProtKB/TrEMBL
      A0A8I3P9L5, A0A8P0TTB2
      Conserved Domains (3) summary
      cd07225
      Location:946 → 1251
      Pat_PNPLA6_PNPLA7; Patatin-like phospholipase domain containing protein 6 and protein 7
      cd12087
      Location:42 → 79
      TM_EGFR-like; Transmembrane domain of the Epidermal Growth Factor Receptor family of Protein Tyrosine Kinases
      cd00038
      Location:620 → 728
      CAP_ED; effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO ...
    Nucleotide Protein
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