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    trub2 TruB pseudouridine (psi) synthase family member 2 [ Xenopus tropicalis (tropical clawed frog) ]

    Gene ID: 496499, updated on 9-Dec-2024

    Summary

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    Official Symbol
    trub2provided by Xenbase
    Official Full Name
    TruB pseudouridine (psi) synthase family member 2provided by Xenbase
    Primary source
    Xenbase:XB-GENE-996199
    See related
    Ensembl:ENSXETG00000044187 AllianceGenome:Xenbase:XB-GENE-996199
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Xenopus tropicalis
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana
    Summary
    Predicted to enable pseudouridine synthase activity. Predicted to act upstream of or within mRNA processing; pseudouridine synthesis; and tRNA processing. Predicted to be located in mitochondrial matrix. Orthologous to human TRUB2 (TruB pseudouridine synthase family member 2). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    human mouse all
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    Genomic context

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    See trub2 in Genome Data Viewer
    Location:
    chromosome: 8
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    104 current UCB_Xtro_10.0 (GCF_000004195.4) 8 NC_030684.2 (3152744..3163448, complement)
    103 previous assembly Xenopus_tropicalis_v9.1 (GCF_000004195.3) 8 NC_030684.1 (381893..395449, complement)

    Chromosome 8 - NC_030684.2Genomic Context describing neighboring genes Neighboring gene zinc finger MYND-type containing 19 Neighboring gene endothelial differentiation related factor 1 Neighboring gene coenzyme Q4 Neighboring gene uncharacterized LOC100485040 Neighboring gene PAXX, non-homologous end joining factor

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Genetic and genomic tools for Xenopus research: The NIH Xenopus initiative. Klein SL, et al. Dev Dyn, 2002 Dec. PMID 12454917
    2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by Xenbase

    Function Evidence Code Pubs
    enables RNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables isomerase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables pseudouridine synthase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables pseudouridine synthase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    enables tRNA pseudouridine(55) synthase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within RNA processing IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within mRNA processing IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within pseudouridine synthesis IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within tRNA processing IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in mitochondrial matrix IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in mitochondrion IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    pseudouridylate synthase TRUB2, mitochondrial; mitochondrial mRNA pseudouridine synthase Trub2
    Names
    TruB pseudouridine (psi) synthase homolog 2
    probable tRNA pseudouridine synthase 2
    psi55 synthase TRUB2
    tRNA pseudouridine 55 synthase TRUB2
    truB pseudouridine synthase homolog 2
    NP_001011086.1
    XP_031746258.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001011086.1 → NP_001011086.1  pseudouridylate synthase TRUB2, mitochondrial

      See identical proteins and their annotated locations for NP_001011086.1

      Status: PROVISIONAL

      Source sequence(s)
      BC084478
      UniProtKB/Swiss-Prot
      Q5XGG2
      Related
      ENSXETP00000113948.1, ENSXETT00000107503.1
      Conserved Domains (1) summary
      cd02868
      Location:14 → 286
      PseudoU_synth_hTruB2_like; Pseudouridine synthase, humanTRUB2_like

    RefSeqs of Annotated Genomes: Xenopus tropicalis Annotation Release 104 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference UCB_Xtro_10.0 Primary Assembly

    Genomic

    1. NC_030684.2 Reference UCB_Xtro_10.0 Primary Assembly

      Range
      3152744..3163448 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_031890398.1 → XP_031746258.1  mitochondrial mRNA pseudouridine synthase Trub2 isoform X1

      UniProtKB/TrEMBL
      A0A803K0U3
      Conserved Domains (1) summary
      cd02868
      Location:14 → 286
      PseudoU_synth_hTruB2_like; Pseudouridine synthase, humanTRUB2_like
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q5XGG2.1 GenPept UniProtKB/Swiss-Prot:Q5XGG2

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.