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    murD UDP-N-acetylmuramoyl-L-alanine--D-glutamate ligase [ Staphylococcus epidermidis ]

    Gene ID: 50019003, updated on 3-Dec-2024

    Summary

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    Gene symbol
    murD
    Gene description
    UDP-N-acetylmuramoyl-L-alanine--D-glutamate ligase
    Locus tag
    EQW00_RS08325
    Gene type
    protein coding
    Organism
    Staphylococcus epidermidis (strain: ATCC 14990, culture-collection: ATCC:14990, type-material: type strain of Staphylococcus epidermidis)
    Lineage
    Bacteria; Bacillota; Bacilli; Bacillales; Staphylococcaceae; Staphylococcus
    Old locus tag
    EQW00_08330
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    Genomic context

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    NZ_CP035288.1Genomic Context describing neighboring genes Neighboring gene cell division protein FtsA Neighboring gene FtsQ-type POTRA domain-containing protein Neighboring gene phospho-N-acetylmuramoyl-pentapeptide-transferase Neighboring gene penicillin-binding protein Neighboring gene cell division protein FtsL

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NZ_CP035288.1

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Combined antibiotic stewardship and infection control measures to contain the spread of linezolid-resistant Staphylococcus epidermidis in an intensive care unit. Papan C, et al. Antimicrob Resist Infect Control, 2021 Jun 30. PMID 34193293, Free PMC Article
    2. Determination of the MurD mechanism through crystallographic analysis of enzyme complexes. Bertrand JA, et al. J Mol Biol, 1999 Jun 11. PMID 10356330
    3. The biology of Mur ligases as an antibacterial target. Kouidmi I, et al. Mol Microbiol, 2014 Oct. PMID 25130693
    4. Crystal structure of UDP-N-acetylmuramoyl-L-alanine:D-glutamate ligase from Escherichia coli. Bertrand JA, et al. EMBO J, 1997 Jun 16. PMID 9218784, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    General protein information

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    Preferred Names
    UDP-N-acetylmuramoyl-L-alanine--D-glutamate ligase
    WP_001830127.1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NZ_CP035288.1 Reference assembly

      Range
      1725489..1726838 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. WP_001830127.1 MULTISPECIES: UDP-N-acetylmuramoyl-L-alanine--D-glutamate ligase [Staphylococcus]

      See identical proteins and their annotated locations for WP_001830127.1

      UniProtKB/Swiss-Prot
      Q8CSX6
      UniProtKB/TrEMBL
      A0A4V2KVE4, A0A9Q5JME1
      Conserved Domains (1) summary
      PRK02472
      Location:5 → 448
      murD; UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase; Provisional
    Nucleotide Protein
    Heading Accession and Version

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