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    YES1 YES proto-oncogene 1, Src family tyrosine kinase [ Bos taurus (domestic cattle) ]

    Gene ID: 507632, updated on 27-Dec-2024

    Summary

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    Official Symbol
    YES1provided by VGNC
    Official Full Name
    YES proto-oncogene 1, Src family tyrosine kinaseprovided by VGNC
    Primary source
    VGNC:VGNC:37022
    See related
    BGD:BT10645; Ensembl:ENSBTAG00000001523
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Orthologs
    human mouse all
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    Genomic context

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    See YES1 in Genome Data Viewer
    Location:
    chromosome: 24
    Exon count:
    14
    Annotation release Status Assembly Chr Location
    RS_2024_12 current ARS-UCD2.0 (GCF_002263795.3) 24 NC_037351.1 (35592010..35656645, complement)

    Chromosome 24 - NC_037351.1Genomic Context describing neighboring genes Neighboring gene clusterin like 1 Neighboring gene enolase superfamily member 1 Neighboring gene thymidylate synthetase Neighboring gene adenylate cyclase activating polypeptide 1 Neighboring gene elongation factor 1-alpha 1-like

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037351.1 Chromosome 24 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Dominette sequence data
    • BioProject: PRJNA294306
    • Analysis date: Tue Dec 17 08:57:05 2024

    Bibliography

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    Related articles in PubMed

    1. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables non-membrane spanning protein tyrosine kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables signaling receptor binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in cell differentiation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in cell surface receptor protein tyrosine kinase signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in innate immune response IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in protein phosphorylation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in extrinsic component of cytoplasmic side of plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    tyrosine-protein kinase Yes
    Names
    v-yes-1 Yamaguchi sarcoma viral oncogene homolog 1
    NP_001094530.1
    XP_015315572.1
    XP_059736761.1
    XP_059736762.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001101060.1 → NP_001094530.1  tyrosine-protein kinase Yes

      See identical proteins and their annotated locations for NP_001094530.1

      Status: PROVISIONAL

      Source sequence(s)
      BC151348
      UniProtKB/TrEMBL
      A0AAA9RZL9, A7MB57
      Related
      ENSBTAP00000001995.6, ENSBTAT00000001995.7
      Conserved Domains (3) summary
      cd09933
      Location:152 → 251
      SH2_Src_family; Src homology 2 (SH2) domain found in the Src family of non-receptor tyrosine kinases
      cd12007
      Location:92 → 149
      SH3_Yes; Src homology 3 domain of Yes Protein Tyrosine Kinase
      cd05069
      Location:262 → 540
      PTKc_Yes; Catalytic domain of the Protein Tyrosine Kinase, Yes

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2024_12

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037351.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      35592010..35656645 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_059880779.1 → XP_059736762.1  tyrosine-protein kinase Yes isoform X1

      UniProtKB/TrEMBL
      A0AAA9RZL9, A7MB57
      Related
      ENSBTAP00000076538.1, ENSBTAT00000121264.1

    2. XM_059880778.1 → XP_059736761.1  tyrosine-protein kinase Yes isoform X1

      UniProtKB/TrEMBL
      A0AAA9RZL9, A7MB57

    3. XM_015460086.3 → XP_015315572.1  tyrosine-protein kinase Yes isoform X1

      UniProtKB/TrEMBL
      A0AAA9RZL9, A7MB57
      Conserved Domains (3) summary
      cd09933
      Location:152 → 251
      SH2_Src_family; Src homology 2 (SH2) domain found in the Src family of non-receptor tyrosine kinases
      cd12007
      Location:92 → 149
      SH3_Yes; Src homology 3 domain of Yes Protein Tyrosine Kinase
      cd05069
      Location:262 → 540
      PTKc_Yes; Catalytic domain of the Protein Tyrosine Kinase, Yes
    Nucleotide Protein Strain
    Heading Accession and Version

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