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    DELE1 DAP3 binding cell death enhancer 1 [ Bos taurus (domestic cattle) ]

    Gene ID: 513834, updated on 1-Jan-2025

    Summary

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    Official Symbol
    DELE1provided by VGNC
    Official Full Name
    DAP3 binding cell death enhancer 1provided by VGNC
    Primary source
    VGNC:VGNC:50135
    See related
    Ensembl:ENSBTAG00000008435
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Also known as
    DELE; KIAA0141
    Orthologs
    human mouse all
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    Genomic context

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    See DELE1 in Genome Data Viewer
    Location:
    chromosome: 7
    Exon count:
    13
    Annotation release Status Assembly Chr Location
    RS_2024_12 current ARS-UCD2.0 (GCF_002263795.3) 7 NC_037334.1 (52989035..53004024)

    Chromosome 7 - NC_037334.1Genomic Context describing neighboring genes Neighboring gene protocadherin 1 Neighboring gene uncharacterized LOC104969197 Neighboring gene protocadherin 12 Neighboring gene ring finger protein 14

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037334.1 Chromosome 7 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Dominette sequence data
    • BioProject: PRJNA294306
    • Analysis date: Tue Dec 17 08:57:05 2024

    Bibliography

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    Related articles in PubMed

    1. Identification of DELE, a novel DAP3-binding protein which is crucial for death receptor-mediated apoptosis induction. Harada T, et al. Apoptosis, 2010 Oct. PMID 20563667
    2. Sequence evaluation of four pooled-tissue normalized bovine cDNA libraries and construction of a gene index for cattle. Smith TP, et al. Genome Res, 2001 Apr. PMID 11282978, Free PMC Article
    3. Characterization of 954 bovine full-CDS cDNA sequences. Harhay GP, et al. BMC Genomics, 2005 Nov 23. PMID 16305752, Free PMC Article
    4. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    5. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Functionally characterizes the human homolog as a DAP3-binding protein involved in apoptosis mediated by death receptors.
      Title: Identification of DELE, a novel DAP3-binding protein which is crucial for death receptor-mediated apoptosis induction.
    Submit: New GeneRIF Correction

    General gene information

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    Homology

    Clone Names

    • KIAA0141, MGC139304

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in extrinsic apoptotic signaling pathway via death domain receptors IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in mitochondrion IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    death ligand signal enhancer

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001024535.1 → NP_001019706.1  death ligand signal enhancer

      See identical proteins and their annotated locations for NP_001019706.1

      Status: PROVISIONAL

      Source sequence(s)
      BT021716
      UniProtKB/TrEMBL
      F1N0X1, Q58D81
      Related
      ENSBTAP00000011098.3, ENSBTAT00000011098.5
      Conserved Domains (3) summary
      smart00671
      Location:281 → 316
      SEL1; Sel1-like repeats
      COG0790
      Location:203 → 448
      TPR; TPR repeat [Signal transduction mechanisms]
      sd00010
      Location:264 → 293
      SLR; SLR repeat [structural motif]

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2024_12

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037334.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      52989035..53004024
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version

    Gene LinkOut

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    Research Materials