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    DENND10P1 DENND10 pseudogene 1 [ Homo sapiens (human) ]

    Gene ID: 55855, updated on 10-Dec-2024

    Summary

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    Official Symbol
    DENND10P1provided by HGNC
    Official Full Name
    DENND10 pseudogene 1provided by HGNC
    Primary source
    HGNC:HGNC:30886
    See related
    AllianceGenome:HGNC:30886
    Gene type
    pseudo
    RefSeq status
    VALIDATED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    HT011; FAM45B; FAM45BP
    Summary
    Predicted to enable guanyl-nucleotide exchange factor activity and small GTPase binding activity. Predicted to be involved in protein transport and regulation of early endosome to late endosome transport. Predicted to be located in endosome. Predicted to be active in late endosome. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See DENND10P1 in Genome Data Viewer
    Location:
    Xq26.1
    Exon count:
    1
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCh38.p14 (GCF_000001405.40) X NC_000023.11 (130494941..130497448)
    RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) X NC_060947.1 (128814765..128817272)
    RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) X NC_000023.10 (129628915..129631422)

    Chromosome X - NC_000023.11Genomic Context describing neighboring genes Neighboring gene RNA binding motif protein X-linked 2 Neighboring gene fibrous sheath interacting protein 2 like, pseudogene Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chrX:129651017-129651626 Neighboring gene uncharacterized LOC105373336 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 29942 Neighboring gene H3K4me1 hESC enhancer GRCh37_chrX:129706680-129707280 Neighboring gene H3K4me1 hESC enhancer GRCh37_chrX:129707281-129707881 Neighboring gene GATA motif-containing MPRA enhancer 234 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 29943 Neighboring gene SPRING1 pseudogene 2 Neighboring gene ecto-NOX disulfide-thiol exchanger 2

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Gene expression profiling in the human hypothalamus-pituitary-adrenal axis and full-length cDNA cloning. Hu RM, et al. Proc Natl Acad Sci U S A, 2000 Aug 15. PMID 10931946, Free PMC Article
    2. hORFeome v3.1: a resource of human open reading frames representing over 10,000 human genes. Lamesch P, et al. Genomics, 2007 Mar. PMID 17207965, Free PMC Article
    3. Histone deacetylase inhibitors inhibit cervical cancer growth through Parkin acetylation-mediated mitophagy. Sun X, et al. Acta Pharm Sin B, 2022 Feb. PMID 35256949, Free PMC Article
    4. TRIM67 drives tumorigenesis in oligodendrogliomas through Rho GTPase-dependent membrane blebbing. Demirdizen E, et al. Neuro Oncol, 2023 Jun 2. PMID 36215168, Free PMC Article
    5. Architecture of the human interactome defines protein communities and disease networks. Huttlin EL, et al. Nature, 2017 May 25. PMID 28514442, Free PMC Article

    See all (8) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Phenotypes

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    Review eQTL and phenotype association data in this region using PheGenI

    Variation

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    See studies and variants in dbVar

    See Variation Viewer (GRCh37.p13)

    See Variation Viewer (GRCh38)

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Other Names

    • family with sequence similarity 45 member B, pseudogene
    • family with sequence similarity 45, member A pseudogene
    • family with sequence similarity 45, member B

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    Genomic

    1. NG_021369.1 RefSeqGene

      Range
      5001..7508
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    RNA

    1. NR_027141.2 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      Z82195

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000023.11 Reference GRCh38.p14 Primary Assembly

      Range
      130494941..130497448
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060947.1 Alternate T2T-CHM13v2.0

      Range
      128814765..128817272
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Suppressed Reference Sequence(s)

    The following Reference Sequences have been suppressed. Explain

    1. NM_018472.2: Suppressed sequence

      Description
      NM_018472.2: This RefSeq was permanently suppressed because it is now thought that this gene is a pseudogene.
    Nucleotide Protein
    Heading Accession and Version

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