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    HCST hematopoietic cell signal transducer [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 574152, updated on 17-Aug-2024

    Summary

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    Official Symbol
    HCSTprovided by VGNC
    Official Full Name
    hematopoietic cell signal transducerprovided by VGNC
    Primary source
    VGNC:VGNC:73181
    See related
    Ensembl:ENSMMUG00000019758
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Also known as
    DAP10
    Orthologs
    human mouse all
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    Genomic context

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    See HCST in Genome Data Viewer
    Location:
    chromosome: 19
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 19 NC_041772.1 (35315049..35319397)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 19 NC_027911.1 (31823451..31826030)

    Chromosome 19 - NC_041772.1Genomic Context describing neighboring genes Neighboring gene kirre like nephrin family adhesion molecule 2 Neighboring gene amyloid beta precursor like protein 1 Neighboring gene NFKB inhibitor delta Neighboring gene transmembrane immune signaling adaptor TYROBP Neighboring gene leucine rich repeat and fibronectin type III domain containing 3

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables phosphatidylinositol 3-kinase binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables signaling receptor binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of immune response IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    hematopoietic cell signal transducer
    Names
    DNAX-activation protein 10
    membrane protein DAP10

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001032835.2 → NP_001028007.1  hematopoietic cell signal transducer precursor

      See identical proteins and their annotated locations for NP_001028007.1

      Status: VALIDATED

      Source sequence(s)
      AF321610
      UniProtKB/Swiss-Prot
      Q8WNQ9
      Related
      ENSMMUP00000025981.2, ENSMMUT00000027772.3
      Conserved Domains (1) summary
      pfam07213
      Location:1 → 79
      DAP10; DAP10 membrane protein

    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041772.1 Reference Mmul_10 Primary Assembly

      Range
      35315049..35319397
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_028838319.1 → XP_028694152.1  hematopoietic cell signal transducer isoform X3

      UniProtKB/TrEMBL
      F7AQW3
      Conserved Domains (1) summary
      pfam07213
      Location:1 → 79
      DAP10; DAP10 membrane protein

    2. XM_015123559.2 → XP_014979045.2  hematopoietic cell signal transducer isoform X1

      Conserved Domains (1) summary
      pfam07213
      Location:24 → 102
      DAP10; DAP10 membrane protein

    3. XM_015123560.2 → XP_014979046.2  hematopoietic cell signal transducer isoform X2

      Conserved Domains (1) summary
      pfam07213
      Location:24 → 101
      DAP10; DAP10 membrane protein
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8WNQ9.1 GenPept UniProtKB/Swiss-Prot:Q8WNQ9

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