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    vraR two-component system response regulator VraR [ Staphylococcus lugdunensis ]

    Gene ID: 58091751, updated on 3-Mar-2024

    Summary

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    Gene symbol
    vraR
    Gene description
    two-component system response regulator VraR
    Locus tag
    AL499_RS11825
    Gene type
    protein coding
    Organism
    Staphylococcus lugdunensis (strain: FDAARGOS_141, nat-host: Homo sapiens, culture-collection: FDA:FDAARGOS_141)
    Lineage
    Bacteria; Bacillota; Bacilli; Bacillales; Staphylococcaceae; Staphylococcus
    Old locus tag
    AL499_11830
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    Genomic context

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    NZ_CP014022.1Genomic Context describing neighboring genes Neighboring gene hypothetical protein Neighboring gene cell wall-active antibiotics response protein LiaF Neighboring gene sensor histidine kinase Neighboring gene YihY/virulence factor BrkB family protein Neighboring gene YtxH domain-containing protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NZ_CP014022.1

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The dimerization interface in VraR is essential for induction of the cell wall stress response in Staphylococcus aureus: a potential druggable target. Tajbakhsh G, et al. BMC Microbiol, 2019 Jul 5. PMID 31277575, Free PMC Article
    2. VraR Binding to the Promoter Region of agr Inhibits Its Function in Vancomycin-Intermediate Staphylococcus aureus (VISA) and Heterogeneous VISA. Dai Y, et al. Antimicrob Agents Chemother, 2017 May. PMID 28289032, Free PMC Article
    3. Whole-Genome Sequencing of Seven Strains of Staphylococcus lugdunensis Allows Identification of Mobile Genetic Elements. Argemi X, et al. Genome Biol Evol, 2017 May 1. PMID 28444231, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General protein information

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    Preferred Names
    two-component system response regulator VraR

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NZ_CP014022.1 Reference assembly

      Range
      2516850..2517479
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. WP_002461333.1 MULTISPECIES: two-component system response regulator VraR [Staphylococcus]

      See identical proteins and their annotated locations for WP_002461333.1

      UniProtKB/TrEMBL
      A0A133QAY4, A0A853V325
      Conserved Domains (1) summary
      COG2197
      Location:3 → 209
      CitB; DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains [Signal transduction mechanisms, Transcription]
    Nucleotide Protein
    Heading Accession and Version