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    ftsH ATP-dependent zinc metalloprotease FtsH [ Enterococcus faecalis EnGen0336 ]

    Gene ID: 60892756, updated on 11-Dec-2024

    Summary

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    Gene symbol
    ftsH
    Gene description
    ATP-dependent zinc metalloprotease FtsH
    Locus tag
    WMS_RS05295
    Gene type
    protein coding
    Organism
    Enterococcus faecalis EnGen0336 (strain: T5)
    Lineage
    Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales; Enterococcaceae; Enterococcus
    Old locus tag
    WMS_00438
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    Genomic context

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    NZ_KB944666.1Genomic Context describing neighboring genes Neighboring gene tRNA lysidine(34) synthetase TilS Neighboring gene hypoxanthine phosphoribosyltransferase Neighboring gene Hsp33 family molecular chaperone HslO Neighboring gene tRNA dihydrouridine synthase DusB

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NZ_KB944666.1

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. An essential protease, FtsH, influences daptomycin resistance acquisition in Enterococcus faecalis. Nair ZJ, et al. Mol Microbiol, 2024 May. PMID 38527904
    2. When, how and why? Regulated proteolysis by the essential FtsH protease in Escherichia coli. Bittner LM, et al. Biol Chem, 2017 May 1. PMID 28085670
    3. FtsH protease-mediated regulation of various cellular functions. Okuno T, et al. Subcell Biochem, 2013. PMID 23479437
    4. Functional characterization of AAA family FtsH protease of Mycobacterium tuberculosis. Srinivasan R, et al. FEMS Microbiol Lett, 2006 Jun. PMID 16684108

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. An essential protease, FtsH, influences daptomycin resistance acquisition in Enterococcus faecalis.
      Title: An essential protease, FtsH, influences daptomycin resistance acquisition in Enterococcus faecalis.
    Submit: New GeneRIF Correction

    General protein information

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    Preferred Names
    ATP-dependent zinc metalloprotease FtsH

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NZ_KB944666.1 Reference assembly

      Range
      474256..476412
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. WP_002363441.1 MULTISPECIES: ATP-dependent zinc metalloprotease FtsH [Enterococcus]

      See identical proteins and their annotated locations for WP_002363441.1

      UniProtKB/TrEMBL
      A0A1B4XKX5, A0A640MUG0, Q839B1, R3L5X7, V7ZQI9
      Conserved Domains (3) summary
      TIGR01241
      Location:143 → 626
      FtsH_fam; ATP-dependent metalloprotease FtsH
      pfam06480
      Location:26 → 126
      FtsH_ext; FtsH Extracellular
      NF033930
      Location:597 → 708
      pneumo_PspA; pneumococcal surface protein A
    Nucleotide Protein
    Heading Accession and Version