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    WMS_RS08475 penicillin-binding protein [ Enterococcus faecalis EnGen0336 ]

    Gene ID: 60893378, updated on 11-Dec-2024

    Summary

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    Gene symbol
    WMS_RS08475
    Gene description
    penicillin-binding protein
    Locus tag
    WMS_RS08475
    Gene type
    protein coding
    Organism
    Enterococcus faecalis EnGen0336 (strain: T5)
    Lineage
    Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales; Enterococcaceae; Enterococcus
    Old locus tag
    WMS_01071
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    Genomic context

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    NZ_KB944666.1Genomic Context describing neighboring genes Neighboring gene 16S rRNA (cytosine(1402)-N(4))-methyltransferase RsmH Neighboring gene cell division protein FtsL Neighboring gene phospho-N-acetylmuramoyl-pentapeptide-transferase Neighboring gene UDP-N-acetylmuramoyl-L-alanine--D-glutamate ligase

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NZ_KB944666.1

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Peptidoglycan biosynthesis and remodeling revisited. Shaku M, et al. Adv Appl Microbiol, 2020. PMID 32762868
    2. Penicillin binding protein 2a: An overview and a medicinal chemistry perspective. Shalaby MW, et al. Eur J Med Chem, 2020 Aug 1. PMID 32442851

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    General protein information

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    Preferred Names
    penicillin-binding protein

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NZ_KB944666.1 Reference assembly

      Range
      1109629..1111857
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      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. WP_002381310.1 MULTISPECIES: penicillin-binding protein [Enterococcus]

      See identical proteins and their annotated locations for WP_002381310.1

      UniProtKB/TrEMBL
      A0A1Y0LYK0, A0AAJ2CXZ9, Q836V7
      Conserved Domains (4) summary
      cd06575
      Location:687 → 739
      PASTA_Pbp2x-like_2; PASTA domain of PBP2x-like proteins, second repeat. Penicillin-binding proteins (PBPs) are the major targets for beta-lactam antibiotics, like penicillins and cephalosporins. Beta-lactam antibiotics specifically inhibit transpeptidase activity by ...
      cd06576
      Location:629 → 683
      PASTA_Pbp2x-like_1; PASTA domain of PBP2x-like proteins, first repeat. Penicillin-binding proteins (PBPs) are the major targets for beta-lactam antibiotics, like penicillins and cephalosporins. Beta-lactam antibiotics specifically inhibit transpeptidase activity by ...
      COG0768
      Location:9 → 618
      FtsI; Cell division protein FtsI/penicillin-binding protein 2 [Cell cycle control, cell division, chromosome partitioning, Cell wall/membrane/envelope biogenesis]
      sd00037
      Location:629 → 682
      PASTA; PASTA domain [structural motif]
    Nucleotide Protein
    Heading Accession and Version

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