U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination
    • Showing Current items.

    spoIVFB stage IV sporulation intramembrane metalloprotease SpoIVFB [ Bacillus toyonensis ]

    Gene ID: 64185755, updated on 1-Dec-2024

    Summary

    Go to the top of the page Help
    Gene symbol
    spoIVFB
    Gene description
    stage IV sporulation intramembrane metalloprotease SpoIVFB
    Locus tag
    I0K03_RS21715
    Gene type
    protein coding
    Organism
    Bacillus toyonensis (strain: P18)
    Lineage
    Bacteria; Bacillati; Bacillota; Bacilli; Bacillales; Bacillaceae; Bacillus; Bacillus cereus group
    Old locus tag
    I0K03_21715
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help

    NZ_CP064875.1Genomic Context describing neighboring genes Neighboring gene Rne/Rng family ribonuclease Neighboring gene 50S ribosomal protein L21 Neighboring gene stage IV sporulation protein SpoIVFA Neighboring gene septum site-determining protein MinD Neighboring gene septum site-determining protein MinC

    Genomic regions, transcripts, and products

    Go to the top of the page Help
    Genomic Sequence:
    NZ_CP064875.1

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Interaction of intramembrane metalloprotease SpoIVFB with substrate Pro-σ(K). Halder S, et al. Proc Natl Acad Sci U S A, 2017 Dec 12. PMID 29180425, Free PMC Article
    2. Complex Formed between Intramembrane Metalloprotease SpoIVFB and Its Substrate, Pro-σK. Zhang Y, et al. J Biol Chem, 2016 May 6. PMID 26953342, Free PMC Article
    3. Intramembrane proteolytic cleavage of a membrane-tethered transcription factor by a metalloprotease depends on ATP. Zhou R, et al. Proc Natl Acad Sci U S A, 2009 Sep 22. PMID 19805276, Free PMC Article
    4. A branched pathway governing the activation of a developmental transcription factor by regulated intramembrane proteolysis. Campo N, et al. Mol Cell, 2006 Jul 7. PMID 16818230
    5. Evidence that SpoIVFB is a novel type of membrane metalloprotease governing intercompartmental communication during Bacillus subtilis sporulation. Yu YT, et al. J Bacteriol, 2000 Jun. PMID 10809718, Free PMC Article

    See all (9) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General protein information

    Go to the top of the page Help
    Preferred Names
    stage IV sporulation intramembrane metalloprotease SpoIVFB
    WP_000598976.1

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NZ_CP064875.1 Reference assembly

      Range
      4288684..4289544 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. WP_000598976.1 MULTISPECIES: stage IV sporulation intramembrane metalloprotease SpoIVFB [Bacillus]

      See identical proteins and their annotated locations for WP_000598976.1

      UniProtKB/TrEMBL
      A0A1D3PN63, A0A1V6LMF2, A0A8I1KLF4, A0AAJ1P0K0
      Conserved Domains (1) summary
      cd06161
      Location:10 → 204
      S2P-M50_SpoIVFB; SpoIVFB Site-2 protease (S2P), a zinc metalloprotease (MEROPS family M50B), regulates intramembrane proteolysis (RIP), and is involved in the pro-sigmaK pathway of bacterial spore formation. SpoIVFB (sporulation protein, stage IV cell wall formation, F ...
    Nucleotide Protein
    Heading Accession and Version