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    HNRNPCL3 heterogeneous nuclear ribonucleoprotein C like 3 [ Homo sapiens (human) ]

    Gene ID: 649330, updated on 27-Nov-2024

    Summary

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    Official Symbol
    HNRNPCL3provided by HGNC
    Official Full Name
    heterogeneous nuclear ribonucleoprotein C like 3provided by HGNC
    Primary source
    HGNC:HGNC:51235
    See related
    Ensembl:ENSG00000277058 AllianceGenome:HGNC:51235
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    HNRNPCL2; HNRNPCL4
    Summary
    Predicted to enable RNA binding activity. Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Nov 2024]
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    Genomic context

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    See HNRNPCL3 in Genome Data Viewer
    Location:
    1p36.21
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 1 NC_000001.11 (13060769..13062878)

    Chromosome 1 - NC_000001.11Genomic Context describing neighboring genes Neighboring gene PRAME family member 28, pseudogene Neighboring gene PRAME family member 27 Neighboring gene PRAME family member 25 Neighboring gene PRAME family member 34, pseudogene

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A newly uncovered group of distantly related lysine methyltransferases preferentially interact with molecular chaperones to regulate their activity. Cloutier P, et al. PLoS Genet, 2013. PMID 23349634, Free PMC Article
    2. MAP4K Interactome Reveals STRN4 as a Key STRIPAK Complex Component in Hippo Pathway Regulation. Seo G, et al. Cell Rep, 2020 Jul 7. PMID 32640226, Free PMC Article
    3. SND1 binds SARS-CoV-2 negative-sense RNA and promotes viral RNA synthesis through NSP9. Schmidt N, et al. Cell, 2023 Oct 26. PMID 37794589, Free PMC Article
    4. STING-Mediated IFI16 Degradation Negatively Controls Type I Interferon Production. Li D, et al. Cell Rep, 2019 Oct 29. PMID 31665637
    5. Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein. Tang X, et al. J Biol Chem, 2024 Jun. PMID 38777146, Free PMC Article

    See all (15) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Phenotypes

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    Find tests for this gene in the NIH Genetic Testing Registry (GTR)

    Review eQTL and phenotype association data in this region using PheGenI

    Variation

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    See variants in ClinVar

    See studies and variants in dbVar

    See Variation Viewer (GRCh38)

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by GOA

    Function Evidence Code Pubs
    enables RNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    heterogeneous nuclear ribonucleoprotein C-like 3
    Names
    Heterogeneous nuclear ribonucleoprotein C-like 4
    heterogeneous nuclear ribonucleoprotein C-like 2
    hnRNP C-like-2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001382358.1 → NP_001369287.1  heterogeneous nuclear ribonucleoprotein C-like 3

      Status: VALIDATED

      Source sequence(s)
      AC245056
      Consensus CDS
      CCDS72705.1
      UniProtKB/Swiss-Prot
      B7ZW38, P0DMR1
      UniProtKB/TrEMBL
      A0A0G2JPF8
      Related
      ENSP00000478017.1, ENST00000617807.3
      Conserved Domains (1) summary
      cl17169
      Location:10 → 93
      RRM_SF; RNA recognition motif (RRM) superfamily

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000001.11 Reference GRCh38.p14 Primary Assembly

      Range
      13060769..13062878
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Reference GRCh38.p14 PATCHES

    Genomic

    1. NW_012132914.1 Reference GRCh38.p14 PATCHES

      Range
      215109..217218
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Reference GRCh38.p14 PATCHES

    Genomic

    1. NW_015495298.1 Reference GRCh38.p14 PATCHES

      Range
      56385..58494
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Suppressed Reference Sequence(s)

    The following Reference Sequences have been suppressed. Explain

    1. NM_001146181.4: Suppressed sequence

      Description
      NM_001146181.4: This RefSeq was removed because currently there is insufficient support for the transcript.
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    B7ZW38.1 GenPept UniProtKB/Swiss-Prot:B7ZW38

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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