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    Scamp4 secretory carrier membrane protein 4 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 65170, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Scamp4provided by RGD
    Official Full Name
    secretory carrier membrane protein 4provided by RGD
    Primary source
    RGD:68354
    See related
    EnsemblRapid:ENSRNOG00000018271 AllianceGenome:RGD:68354
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to be involved in protein transport. Predicted to be located in membrane. Predicted to be active in recycling endosome membrane and trans-Golgi network membrane. Orthologous to human SCAMP4 (secretory carrier membrane protein 4). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Adrenal (RPKM 82.7), Kidney (RPKM 64.5) and 9 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See Scamp4 in Genome Data Viewer
    Location:
    7q11
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 7 NC_086025.1 (9752193..9764614, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 7 NC_051342.1 (9101504..9113929, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 7 NC_005106.4 (11969720..11982141, complement)

    Chromosome 7 - NC_086025.1Genomic Context describing neighboring genes Neighboring gene BTB domain containing 2 Neighboring gene casein kinase 1, gamma 2 Neighboring gene large ribosomal subunit protein eL31-like Neighboring gene adenosine deaminase, tRNA-specific 3 Neighboring gene abhydrolase domain containing 17A, depalmitoylase

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. Expression of the SCAMP-4 gene, a new member of the secretory carrier membrane protein family, is repressed by progesterone in brain regions associated with female sexual behavior. Krebs CJ, et al. Brain Res Mol Brain Res, 2001 Mar 31. PMID 11295240
    2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RGD

    Process Evidence Code Pubs
    involved_in protein transport IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in protein transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in reproductive behavior NAS
    Non-traceable Author Statement
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in recycling endosome membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in trans-Golgi network membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    secretory carrier-associated membrane protein 4
    Names
    SCAMP-4

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_031725.2 → NP_113913.2  secretory carrier-associated membrane protein 4

      Status: PROVISIONAL

      Source sequence(s)
      JAXUCZ010000007
      UniProtKB/Swiss-Prot
      Q9ET20
      UniProtKB/TrEMBL
      A6K8I7, A6K8I8, Q5EAN5
      Related
      ENSRNOP00000089473.1, ENSRNOT00000096768.2
      Conserved Domains (1) summary
      pfam04144
      Location:5 → 179
      SCAMP; SCAMP family

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086025.1 Reference GRCr8

      Range
      9752193..9764614 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006240999.3 → XP_006241061.1  secretory carrier-associated membrane protein 4 isoform X1

      See identical proteins and their annotated locations for XP_006241061.1

      UniProtKB/Swiss-Prot
      Q9ET20
      UniProtKB/TrEMBL
      A6K8I7, A6K8I8, Q5EAN5
      Conserved Domains (1) summary
      pfam04144
      Location:5 → 179
      SCAMP; SCAMP family

    2. XM_017595101.3 → XP_017450590.1  secretory carrier-associated membrane protein 4 isoform X1

      UniProtKB/Swiss-Prot
      Q9ET20
      UniProtKB/TrEMBL
      A6K8I7, A6K8I8, Q5EAN5
      Conserved Domains (1) summary
      pfam04144
      Location:5 → 179
      SCAMP; SCAMP family

    3. XM_063264221.1 → XP_063120291.1  secretory carrier-associated membrane protein 4 isoform X2

      UniProtKB/TrEMBL
      A6K8I9
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9ET20.1 GenPept UniProtKB/Swiss-Prot:Q9ET20

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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