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    hemC hydroxymethylbilane synthase [ Clostridioides difficile ]

    Gene ID: 66355881, updated on 15-Dec-2024

    Summary

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    Gene symbol
    hemC
    Gene description
    hydroxymethylbilane synthase
    Locus tag
    KNZ77_RS17215
    Gene type
    protein coding
    Organism
    Clostridioides difficile (strain: S-0253, nat-host: Homo sapiens)
    Lineage
    Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
    Old locus tag
    KNZ77_17215
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    Genomic context

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    NZ_CP076401.1Genomic Context describing neighboring genes Neighboring gene bifunctional precorrin-2 dehydrogenase/sirohydrochlorin ferrochelatase Neighboring gene porphobilinogen synthase Neighboring gene uroporphyrinogen-III C-methyltransferase Neighboring gene cobalt-factor II C(20)-methyltransferase Neighboring gene precorrin-6A reductase Neighboring gene precorrin-3B C(17)-methyltransferase

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NZ_CP076401.1

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The three-dimensional structure of Escherichia coli porphobilinogen deaminase at 1.76-A resolution. Louie GV, et al. Proteins, 1996 May. PMID 8727319
    2. Purification, characterization, crystallisation and X-ray analysis of selenomethionine-labelled hydroxymethylbilane synthase from Escherichia coli. Hädener A, et al. Eur J Biochem, 1993 Feb 1. PMID 8436121
    3. Cloning and sequencing of some genes responsible for porphyrin biosynthesis from the anaerobic bacterium Clostridium josui. Fujino E, et al. J Bacteriol, 1995 Sep. PMID 7665501, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General protein information

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    Preferred Names
    hydroxymethylbilane synthase
    WP_003425719.1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NZ_CP076401.1 Reference assembly

      Range
      3813880..3814785 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. WP_003425719.1 hydroxymethylbilane synthase [Clostridioides difficile]

      See identical proteins and their annotated locations for WP_003425719.1

      UniProtKB/TrEMBL
      A0A069AG81
      Conserved Domains (1) summary
      COG0181
      Location:1 → 295
      HemC; Porphobilinogen deaminase [Coenzyme transport and metabolism]
    Nucleotide Protein
    Heading Accession and Version