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    KNZ77_RS18265 diguanylate cyclase domain-containing protein [ Clostridioides difficile ]

    Gene ID: 66356091, updated on 15-Dec-2024

    Summary

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    Gene symbol
    KNZ77_RS18265
    Gene description
    diguanylate cyclase domain-containing protein
    Locus tag
    KNZ77_RS18265
    Gene type
    protein coding
    Organism
    Clostridioides difficile (strain: S-0253, nat-host: Homo sapiens)
    Lineage
    Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
    Old locus tag
    KNZ77_18265
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    Genomic context

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    NZ_CP076401.1Genomic Context describing neighboring genes Neighboring gene ABC transporter ATP-binding protein Neighboring gene bacteriocin-associated integral membrane family protein Neighboring gene KDPG and KHG aldolase Neighboring gene 4-hydroxy-tetrahydrodipicolinate synthase

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NZ_CP076401.1

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The atypical two-component sensor kinase Lpl0330 from Legionella pneumophila controls the bifunctional diguanylate cyclase-phosphodiesterase Lpl0329 to modulate bis-(3'-5')-cyclic dimeric GMP synthesis. Levet-Paulo M, et al. J Biol Chem, 2011 Sep 9. PMID 21757706, Free PMC Article
    2. Allosteric control of cyclic di-GMP signaling. Christen B, et al. J Biol Chem, 2006 Oct 20. PMID 16923812
    3. Cell cycle-dependent dynamic localization of a bacterial response regulator with a novel di-guanylate cyclase output domain. Paul R, et al. Genes Dev, 2004 Mar 15. PMID 15075296, Free PMC Article
    4. Cyclic di-guanosine-monophosphate comes of age: a novel secondary messenger involved in modulating cell surface structures in bacteria? Jenal U. Curr Opin Microbiol, 2004 Apr. PMID 15063857
    5. Bacterial signal transduction network in a genomic perspective. Galperin MY. Environ Microbiol, 2004 Jun. PMID 15142243, Free PMC Article

    See all (9) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General protein information

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    Preferred Names
    diguanylate cyclase domain-containing protein
    WP_009898810.1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NZ_CP076401.1 Reference assembly

      Range
      4030665..4033172 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. WP_009898810.1 diguanylate cyclase domain-containing protein [Clostridioides difficile]

      See identical proteins and their annotated locations for WP_009898810.1

      UniProtKB/TrEMBL
      A0A9X8WR64
      Conserved Domains (3) summary
      cd01949
      Location:410 → 564
      GGDEF; Diguanylate-cyclase (DGC) or GGDEF domain
      COG2203
      Location:603 → 757
      FhlA; GAF domain [Signal transduction mechanisms]
      pfam13426
      Location:38 → 128
      PAS_9; PAS domain
    Nucleotide Protein
    Heading Accession and Version