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    pheS phenylalanine--tRNA ligase subunit alpha [ Enterococcus faecium ]

    Gene ID: 66454206, updated on 3-Dec-2024

    Summary

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    Gene symbol
    pheS
    Gene description
    phenylalanine--tRNA ligase subunit alpha
    Locus tag
    E6A31_RS05995
    Gene type
    protein coding
    Organism
    Enterococcus faecium (strain: SRR24, nat-host: Homo sapiens)
    Lineage
    Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae; Enterococcus
    Old locus tag
    E6A31_06410
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    Genomic context

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    NZ_CP038996.1Genomic Context describing neighboring genes Neighboring gene PD-(D/E)XK nuclease family protein Neighboring gene helicase-exonuclease AddAB subunit AddA Neighboring gene helix-turn-helix domain-containing protein Neighboring gene phenylalanine--tRNA ligase subunit beta Neighboring gene tryptophan--tRNA ligase

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NZ_CP038996.1

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Emergence of vancomycin-resistant Enterococcus faecium ST1421 lacking the pstS gene in Korea. Kim HM, et al. Eur J Clin Microbiol Infect Dis, 2020 Jul. PMID 32128641
    2. The role of a novel auxiliary pocket in bacterial phenylalanyl-tRNA synthetase druggability. Abibi A, et al. J Biol Chem, 2014 Aug 1. PMID 24936059, Free PMC Article
    3. Idiosyncrasy and identity in the prokaryotic Phe-system: crystal structure of E. coli phenylalanyl-tRNA synthetase complexed with phenylalanine and AMP. Mermershtain I, et al. Protein Sci, 2011 Jan. PMID 21082706, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    General protein information

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    Preferred Names
    phenylalanine--tRNA ligase subunit alpha
    WP_002295783.1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NZ_CP038996.1 Reference assembly

      Range
      1222578..1223621
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      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. WP_002295783.1 MULTISPECIES: phenylalanine--tRNA ligase subunit alpha [Enterococcus]

      See identical proteins and their annotated locations for WP_002295783.1

      UniProtKB/TrEMBL
      A0A132Z5G9, A0A1E9WBY0, A0A3N3RQX8, A0A829FB74, A0A9P2S721, A0AAV3DNV2, A0AAV3DXS4, A0AAV3GY05, A0AAV3L3Y9
      Conserved Domains (1) summary
      PRK00488
      Location:3 → 344
      pheS; phenylalanyl-tRNA synthetase subunit alpha; Validated
    Nucleotide Protein
    Heading Accession and Version

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