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    E6A31_RS14175 type II toxin-antitoxin system RelE/ParE family toxin [ Enterococcus faecium ]

    Gene ID: 66455833, updated on 30-Mar-2024

    Summary

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    Gene symbol
    E6A31_RS14175
    Gene description
    type II toxin-antitoxin system RelE/ParE family toxin
    Locus tag
    E6A31_RS14175
    Gene type
    protein coding
    Organism
    Enterococcus faecium (strain: SRR24, nat-host: Homo sapiens)
    Lineage
    Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae; Enterococcus
    Old locus tag
    E6A31_15030
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    Genomic context

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    Location:
    plasmid: pSRR24

    NZ_CP038997.1Genomic Context describing neighboring genes Neighboring gene IS6-like element IS1216 family transposase Neighboring gene hypothetical protein Neighboring gene DUF6290 family protein Neighboring gene AAA family ATPase

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NZ_CP038997.1

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Emergence of vancomycin-resistant Enterococcus faecium ST1421 lacking the pstS gene in Korea. Kim HM, et al. Eur J Clin Microbiol Infect Dis, 2020 Jul. PMID 32128641
    2. Evolving new protein-protein interaction specificity through promiscuous intermediates. Aakre CD, et al. Cell, 2015 Oct 22. PMID 26478181, Free PMC Article
    3. Interaction specificity, toxicity and regulation of a paralogous set of ParE/RelE-family toxin-antitoxin systems. Fiebig A, et al. Mol Microbiol, 2010 Jul 1. PMID 20487277, Free PMC Article
    4. A conserved mode of protein recognition and binding in a ParD-ParE toxin-antitoxin complex. Dalton KM, et al. Biochemistry, 2010 Mar 16. PMID 20143871, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General protein information

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    Preferred Names
    type II toxin-antitoxin system RelE/ParE family toxin

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NZ_CP038997.1 Reference assembly

      Range
      103595..103861 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. WP_010729835.1 MULTISPECIES: type II toxin-antitoxin system RelE/ParE family toxin [Enterococcus]

      See identical proteins and their annotated locations for WP_010729835.1

      UniProtKB/TrEMBL
      A0A1A7STW7, A0A829F177
      Conserved Domains (1) summary
      COG2026
      Location:1 → 88
      RelE; mRNA-degrading endonuclease RelE, toxin component of the RelBE toxin-antitoxin system [Defense mechanisms]
    Nucleotide Protein
    Heading Accession and Version