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    Bpifa3 BPI fold containing family A, member 3 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 690402, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Bpifa3provided by RGD
    Official Full Name
    BPI fold containing family A, member 3provided by RGD
    Primary source
    RGD:1596102
    See related
    EnsemblRapid:ENSRNOG00000013778 AllianceGenome:RGD:1596102
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    Splunc3
    Summary
    Predicted to enable lipid binding activity. Orthologous to human BPIFA3 (BPI fold containing family A member 3). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Restricted expression toward (RPKM 171.6) See more
    Orthologs
    human mouse all
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    Genomic context

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    See Bpifa3 in Genome Data Viewer
    Location:
    3q41
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 3 NC_086021.1 (163069905..163079858)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 3 NC_051338.1 (142609748..142619703)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 3 NC_005102.4 (149606925..149616760)

    Chromosome 3 - NC_086021.1Genomic Context describing neighboring genes Neighboring gene translocase of inner mitochondrial membrane 17a-like 1, pseudogene 1 Neighboring gene BPI fold containing family A, member 2F Neighboring gene small nucleolar RNA U13 Neighboring gene uncharacterized LOC134486304 Neighboring gene BPI fold containing family A, member 1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. Systematic nomenclature for the PLUNC/PSP/BSP30/SMGB proteins as a subfamily of the BPI fold-containing superfamily. Bingle CD, et al. Biochem Soc Trans, 2011 Aug. PMID 21787333, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables lipid binding IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    BPI fold-containing family A member 3

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001109588.1 → NP_001103058.1  BPI fold-containing family A member 3 precursor

      See identical proteins and their annotated locations for NP_001103058.1

      Status: PROVISIONAL

      Source sequence(s)
      CH474050
      UniProtKB/TrEMBL
      A6KHX5
      Conserved Domains (1) summary
      pfam01273
      Location:47 → 219
      LBP_BPI_CETP; LBP / BPI / CETP family, N-terminal domain

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086021.1 Reference GRCr8

      Range
      163069905..163079858
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_063284584.1 → XP_063140654.1  BPI fold-containing family A member 3 isoform X5

    2. XM_006235362.5 → XP_006235424.1  BPI fold-containing family A member 3 isoform X2

      UniProtKB/TrEMBL
      D3ZJA2
      Related
      ENSRNOP00000018512.4, ENSRNOT00000018512.6
      Conserved Domains (1) summary
      pfam01273
      Location:47 → 219
      LBP_BPI_CETP; LBP / BPI / CETP family, N-terminal domain

    3. XM_039105883.2 → XP_038961811.1  BPI fold-containing family A member 3 isoform X1

      Related
      ENSRNOP00000102331.1, ENSRNOT00000136651.1
      Conserved Domains (1) summary
      pfam01273
      Location:47 → 207
      LBP_BPI_CETP; LBP / BPI / CETP family, N-terminal domain

    4. XM_039105884.2 → XP_038961812.1  BPI fold-containing family A member 3 isoform X3

      Conserved Domains (1) summary
      cl00188
      Location:1 → 148
      BPI; BPI/LBP/CETP domain; Bactericidal permeability-increasing protein (BPI) / Lipopolysaccharide-binding protein (LBP) / Cholesteryl ester transfer protein (CETP) domain; binds to and neutralizes lipopolysaccharides from the outer membrane of Gram-negative ...

    5. XM_039105886.2 → XP_038961814.1  BPI fold-containing family A member 3 isoform X3

      Conserved Domains (1) summary
      cl00188
      Location:1 → 148
      BPI; BPI/LBP/CETP domain; Bactericidal permeability-increasing protein (BPI) / Lipopolysaccharide-binding protein (LBP) / Cholesteryl ester transfer protein (CETP) domain; binds to and neutralizes lipopolysaccharides from the outer membrane of Gram-negative ...

    6. XM_039105887.2 → XP_038961815.1  BPI fold-containing family A member 3 isoform X4

      Conserved Domains (1) summary
      cl00188
      Location:8 → 122
      BPI; BPI/LBP/CETP domain; Bactericidal permeability-increasing protein (BPI) / Lipopolysaccharide-binding protein (LBP) / Cholesteryl ester transfer protein (CETP) domain; binds to and neutralizes lipopolysaccharides from the outer membrane of Gram-negative ...
    Nucleotide Protein Strain
    Heading Accession and Version

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