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    Zfp429 zinc finger protein 429 [ Mus musculus (house mouse) ]

    Gene ID: 72807, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Zfp429provided by MGI
    Official Full Name
    zinc finger protein 429provided by MGI
    Primary source
    MGI:MGI:1920057
    See related
    Ensembl:ENSMUSG00000078994 AllianceGenome:MGI:1920057
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Rsl2; 2810487A22Rik
    Summary
    Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. Orthologous to human ZNF429 (zinc finger protein 429). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Broad expression in bladder adult (RPKM 2.4), placenta adult (RPKM 2.1) and 21 other tissues See more
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    Genomic context

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    See Zfp429 in Genome Data Viewer
    Location:
    13 B3; 13 34.54 cM
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 13 NC_000079.7 (67535695..67547963, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 13 NC_000079.6 (67388924..67399917, complement)

    Chromosome 13 - NC_000079.7Genomic Context describing neighboring genes Neighboring gene zinc finger protein 595 Neighboring gene zinc finger protein 953 Neighboring gene STARR-positive B cell enhancer ABC_E9880 Neighboring gene predicted gene 17039 Neighboring gene zinc finger protein 456 Neighboring gene STARR-positive B cell enhancer ABC_E4075 Neighboring gene STARR-seq mESC enhancer starr_34900 Neighboring gene zinc finger protein 459 Neighboring gene STARR-seq mESC enhancer starr_34902 Neighboring gene predicted gene, 33787

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. A pair of mouse KRAB zinc finger proteins modulates multiple indicators of female reproduction. Krebs CJ, et al. Biol Reprod, 2010 Apr. PMID 20042539, Free PMC Article
    2. Expansion and diversification of KRAB zinc-finger genes within a cluster including Regulator of sex-limitation 1 and 2. Krebs CJ, et al. Genomics, 2005 Jun. PMID 15885501
    3. Regulator of sex-limitation (Rsl) encodes a pair of KRAB zinc-finger genes that control sexually dimorphic liver gene expression. Krebs CJ, et al. Genes Dev, 2003 Nov 1. PMID 14563677, Free PMC Article
    4. Mouse brain organization revealed through direct genome-scale TF expression analysis. Gray PA, et al. Science, 2004 Dec 24. PMID 15618518
    5. Large-scale gene trapping in C57BL/6N mouse embryonic stem cells. Hansen GM, et al. Genome Res, 2008 Oct. PMID 18799693, Free PMC Article

    See all (16) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables DNA-binding transcription factor activity, RNA polymerase II-specific IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in regulation of transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    zinc finger protein 429
    Names
    regulator of sex-limitation 2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001080941.2 → NP_001074410.2  zinc finger protein 429 isoform 1

      Status: VALIDATED

      Source sequence(s)
      AC154510
      Consensus CDS
      CCDS36714.1
      Related
      ENSMUSP00000105354.2, ENSMUST00000109732.3

    2. NM_001418851.1 → NP_001405780.1  zinc finger protein 429 isoform 1

      Status: VALIDATED

      Source sequence(s)
      AC154510

    3. NM_001418852.1 → NP_001405781.1  zinc finger protein 429 isoform 1

      Status: VALIDATED

      Source sequence(s)
      AC154510

    4. NM_001418853.1 → NP_001405782.1  zinc finger protein 429 isoform 1

      Status: VALIDATED

      Source sequence(s)
      AC154510

    5. NM_001418854.1 → NP_001405783.1  zinc finger protein 429 isoform 1

      Status: VALIDATED

      Source sequence(s)
      AC154510

    6. NM_001418855.1 → NP_001405784.1  zinc finger protein 429 isoform 1

      Status: VALIDATED

      Source sequence(s)
      AC154510

    7. NM_001418856.1 → NP_001405785.1  zinc finger protein 429 isoform 1

      Status: VALIDATED

      Source sequence(s)
      AC154510

    8. NM_001418857.1 → NP_001405786.1  zinc finger protein 429 isoform 2

      Status: VALIDATED

      Source sequence(s)
      AC154510
      UniProtKB/TrEMBL
      A0A286YCH9
      Related
      ENSMUSP00000152989.2, ENSMUST00000224684.2

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000079.7 Reference GRCm39 C57BL/6J

      Range
      67535695..67547963 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_030247430.2 → XP_030103290.1  zinc finger protein 429 isoform X1

      Conserved Domains (3) summary
      smart00349
      Location:2 → 61
      KRAB; krueppel associated box
      COG5048
      Location:131 → 448
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:136 → 156
      ZF_C2H2; C2H2 Zn finger [structural motif]

    2. XM_030247429.2 → XP_030103289.1  zinc finger protein 429 isoform X1

      Conserved Domains (3) summary
      smart00349
      Location:2 → 61
      KRAB; krueppel associated box
      COG5048
      Location:131 → 448
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:136 → 156
      ZF_C2H2; C2H2 Zn finger [structural motif]

    3. XM_036158190.1 → XP_036014083.1  zinc finger protein 429 isoform X1

      Conserved Domains (3) summary
      smart00349
      Location:2 → 61
      KRAB; krueppel associated box
      COG5048
      Location:131 → 448
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:136 → 156
      ZF_C2H2; C2H2 Zn finger [structural motif]

    4. XM_036158189.1 → XP_036014082.1  zinc finger protein 429 isoform X1

      Conserved Domains (3) summary
      smart00349
      Location:2 → 61
      KRAB; krueppel associated box
      COG5048
      Location:131 → 448
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:136 → 156
      ZF_C2H2; C2H2 Zn finger [structural motif]
    Nucleotide Protein Strain
    Heading Accession and Version

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